ATP, UTP, ADP and ADP‐β‐S elicited Ca2+‐signals in cultured aortic smooth muscle cells
although ADP, UDP and ADP‐β‐S gave∼ 40% of the maximal response seen with ATP and …

Background and purpose: P2Y receptors evoke Ca2+ signals in vascular smooth muscle
cells and regulate contraction and proliferation, but the roles of the different P2Y receptor …

Adenine and uridine nucleotides evoke Ca 2+ signals via four subtypes of P2Y receptor in
cultured aortic smooth muscle cells, but the mechanisms underlying the different patterns of …

Previous studies have shown that ATP and UTP are able to stimulate phospholipase C
(PLC) and proliferation in cultured aortic smooth muscle cells. Here we set out to …

Intracellular Ca2+ signals elicited by nucleotide agonists were investigated in primary
cultures of rat cardiac microvascular endothelial cells using the fura-2 technique. UTP …

Depending on the vascular bed considered, the actions of ATP on the endothelium are
mediated by either P2Y or P2U receptors. The two types of receptors seem to coexist on …

Nucleotides regulate various effects including vascular tone. This study was aimed to
characterize P2Y receptors on endothelial cells of the aorta of C57BL6 mice. Five adjacent …

It has previously been shown that ATP and UTP stimulate P2Y receptors in vascular smooth
muscle cells (VSMCs), but the nature of these receptors, in particular the contribution of …

In vascular smooth muscle, extracellular ATP induces an increase in intracellular
[Ca2+]([Ca2+] i). Various agonists have been used to characterize P2-purinoceptor subtypes …

P 2 receptor subtypes and their signaling mechanisms were characterized in dispersed
smooth muscle cells. UTP and ATP stimulated inositol 1, 4, 5-triphosphate formation, Ca 2+ …