Oxidative stress is central to the pathology of several neurodegenerative diseases, including
Parkinson's disease (PD), and therapeutics designed to enhance antioxidant potential could …

Aim: Oxidative stress plays a key role in Parkinson disease (PD), and nuclear transcription
factor related to NF-E2 (Nrf-2) is involved in neuroprotection against PD. The aim of the …

A promising approach to neurotherapeutics involves activating the nuclear-factor-E2-related
factor 2 (Nrf2)/antioxidant response element signaling, which regulates expression of …

Parkinson disease (PD) is a neurodegenerative disorder characterized by a selective loss of
dopaminergic neurons in the substantia nigra, and oxidative stress is thought to contribute to …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by a selective loss
of dopaminergic neurons in the substantia nigra (SN), and oxidative stress is thought to …

Pharmacological activation at the basal ganglia of the transcription factor Nrf2, guardian of
redox homeostasis, holds a strong promise for the slow progression of Parkinson's disease …

Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by cell
loss in the substantia nigra resulting in striatal dopamine depletion. Although the cause of …

Multiple sclerosis (MS) is the most common multifocal inflammatory demyelinating disease
of the central nervous system (CNS). Due to the progressive neurodegenerative nature of …

Chemotherapy agents such as oxaliplatin, cisplatin, paclitaxel, and bortezomib frequently
cause severe peripheral neuropathy and there is currently no effective strategy to prevent …

Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample
empirical evidence suggests that oxidative stress is involved in the pathogenesis of this …