Antioxidants increase blastocyst cryosurvival and viability post-vitrification
TT Truong, DK Gardner - Human reproduction, 2020 - academic.oup.com
STUDY QUESTION What is the effect of antioxidants acetyl-L-carnitine, N-acetyl-L-cysteine
and α-lipoic acid (A3) in vitrification and warming solutions on mouse blastocyst …
and α-lipoic acid (A3) in vitrification and warming solutions on mouse blastocyst …
Antioxidant supplementation of mouse embryo culture or vitrification media support more in-vivo-like gene expression post-transfer
T Truong, AJ Harvey, DK Gardner - Reproductive BioMedicine Online, 2022 - Elsevier
Research question What is the effect on mouse fetal gene expression of combined
antioxidants (acetyl-L-carnitine, N-acetyl-L-cysteine and alpha-lipoic acid; A3) when used in …
antioxidants (acetyl-L-carnitine, N-acetyl-L-cysteine and alpha-lipoic acid; A3) when used in …
Addition of ascorbate during cryopreservation stimulates subsequent embryo development
M Lane, JM Maybach, DK Gardner - Human reproduction, 2002 - academic.oup.com
BACKGROUND: Embryo development following cryopreservation is reduced compared with
fresh embryos. One of the traumas that cryopreservation imparts on embryos is an increase …
fresh embryos. One of the traumas that cryopreservation imparts on embryos is an increase …
Comparative effects of adding β-mercaptoethanol or L-ascorbic acid to culture or vitrification–warming media on IVF porcine embryos
M Castillo-Martín, S Bonet, R Morató… - Reproduction, Fertility …, 2014 - CSIRO Publishing
The aims of the present study were to;(1) determine the effects of supplementation with two
antioxidants during in vitro culture (IVC) on embryo development and quality; and (2) test the …
antioxidants during in vitro culture (IVC) on embryo development and quality; and (2) test the …
Antioxidants improve mouse preimplantation embryo development and viability
TT Truong, YM Soh, DK Gardner - Human Reproduction, 2016 - academic.oup.com
STUDY QUESTION What is the effect of three antioxidants (acetyl-L-carnitine, N-acetyl-L-
cysteine and α-lipoic acid), when used individually and in combination, on mouse embryo …
cysteine and α-lipoic acid), when used individually and in combination, on mouse embryo …
Antioxidant supplementation of culture medium during embryo development and/or after vitrification-warming; which is the most important?
Purpose To determine the most optimal stage for antioxidant supplementation of culture
medium to improve developmental competence, cryotolerance and DNA-fragmentation of …
medium to improve developmental competence, cryotolerance and DNA-fragmentation of …
Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification
T Trapphoff, M Heiligentag, J Simon… - MHR: Basic science …, 2016 - academic.oup.com
STUDY QUESTION Can supplementation of media with a glutathione (GSH) donor,
glutathione ethyl ester (GEE), prior to vitrification protect the mouse oocyte from oxidative …
glutathione ethyl ester (GEE), prior to vitrification protect the mouse oocyte from oxidative …
Impact of vitrification on the mitochondrial activity and redox homeostasis of human oocyte
M Nohales-Córcoles, G Sevillano-Almerich… - Human …, 2016 - academic.oup.com
STUDY QUESTION Do the extreme conditions of vitrification affect mitochondrial health and
reactive oxygen species (ROS) levels of human oocytes? SUMMARY ANSWER Vitrification …
reactive oxygen species (ROS) levels of human oocytes? SUMMARY ANSWER Vitrification …
Reduced levels of intracellular reactive oxygen species and apoptotic status are not correlated with increases in cryotolerance of bovine embryos produced in vitro in …
NAS Rocha-Frigoni, BCS Leão… - Reproduction …, 2014 - CSIRO Publishing
The effects of intracellular (cysteine and β-mercaptoethanol) and extracellular (catalase)
antioxidant supplementation at different times during in vitro production (IVM and/or in vitro …
antioxidant supplementation at different times during in vitro production (IVM and/or in vitro …
Different chromatin and energy/redox responses of mouse morulae and blastocysts to slow freezing and vitrification
B Somoskoi, NA Martino, RA Cardone… - Reproductive Biology …, 2015 - Springer
Background The ability to cryopreserve mammalian embryos has become an integral part of
assisted reproduction, both in human and veterinary medicine. Despite differences in the …
assisted reproduction, both in human and veterinary medicine. Despite differences in the …