Protein export through the bacterial Sec pathway
A Tsirigotaki, J De Geyter, A Economou… - Nature Reviews …, 2017 - nature.com
The general secretory (Sec) pathway comprises an essential, ubiquitous and universal
export machinery for most proteins that integrate into, or translocate through, the plasma …
export machinery for most proteins that integrate into, or translocate through, the plasma …
Following the leader: bacterial protein export through the Sec pathway
A Economou - Trends in Microbiology, 1999 - cell.com
Significant strides have been made during the past 20 years in our understanding of protein
secretion across the bacterial inner membrane. Specialized chaperones select secretory …
secretion across the bacterial inner membrane. Specialized chaperones select secretory …
Breaking on through to the other side: protein export through the bacterial Sec system
More than one-third of cellular proteomes traffic into and across membranes. Bacteria have
invented several sophisticated secretion systems that guide various proteins to …
invented several sophisticated secretion systems that guide various proteins to …
The Sec translocon mediated protein transport in prokaryotes and eukaryotes
K Denks, A Vogt, I Sachelaru, NA Petriman… - Molecular membrane …, 2014 - Taylor & Francis
Protein transport via the Sec translocon represents an evolutionary conserved mechanism
for delivering cytosolically-synthesized proteins to extra-cytosolic compartments. The Sec …
for delivering cytosolically-synthesized proteins to extra-cytosolic compartments. The Sec …
Protein translocation across the bacterial cytoplasmic membrane
AJM Driessen, N Nouwen - Annu. Rev. Biochem., 2008 - annualreviews.org
About 25% to 30% of the bacterial proteins function in the cell envelope or outside of the
cell. These proteins are synthesized in the cytosol, and the vast majority is recognized as a …
cell. These proteins are synthesized in the cytosol, and the vast majority is recognized as a …
The bacterial translocase: a dynamic protein channel complex
J De Keyzer, C Van Der Does… - Cellular and Molecular Life …, 2003 - Springer
The major route of protein translocation in bacteria is the so-called general secretion
pathway (Sec-pathway). This route has been extensively studied in Escherichia coli and …
pathway (Sec-pathway). This route has been extensively studied in Escherichia coli and …
Structure of the SecY complex unlocked by a preprotein mimic
The Sec complex forms the core of a conserved machinery coordinating the passage of
proteins across or into biological membranes. The bacterial complex SecYEG interacts with …
proteins across or into biological membranes. The bacterial complex SecYEG interacts with …
Mechanisms of Sec61/SecY-mediated protein translocation across membranes
E Park, TA Rapoport - Annual review of biophysics, 2012 - annualreviews.org
The Sec61 or SecY channel, a universally conserved protein-conducting channel,
translocates proteins across and integrates proteins into the eukaryotic endoplasmic …
translocates proteins across and integrates proteins into the eukaryotic endoplasmic …
The Sec System: Protein Export in Escherichia coli
JM Crane, LL Randall - EcoSal Plus, 2017 - Am Soc Microbiol
In Escherichia coli, proteins found in the periplasm or the outer membrane are exported from
the cytoplasm by the general secretory, Sec, system before they acquire stably folded …
the cytoplasm by the general secretory, Sec, system before they acquire stably folded …
[HTML][HTML] The Sec-dependent pathway
J Beckwith - Research in microbiology, 2013 - Elsevier
The Sec pathway for export of proteins across the cytoplasmic membrane to the bacterial
periplasm and outer membrane was the first secretion pathway to be discovered in bacteria …
periplasm and outer membrane was the first secretion pathway to be discovered in bacteria …