ABSTRACT The pharmacokinetics (PK)–absorption, distribution, metabolism, and
elimination–and pharmacodynamics (PD) of hypertension medications can be significantly …

Hermida et al Pro Bedtime Dosing of Antihypertensive Medications professionals to ingest it
in the morning. Beyond the assumed, although undocumented, improved adherence …

Background: Independent studies have found that elevated sleep-time blood pressure (BP)
is a better predictor of cardiovascular risk than the awake or 24-h BP means in patients …

Diagnosis of hypertension and clinical decisions regarding its treatment are typically based
upon daytime clinic blood pressure (BP) measurements, occasionally supplemented by …

Several prospective studies consistently report elevated asleep blood pressure (BP) and
blunted sleep-time relative systolic BP (SBP) decline (non-dipping) are jointly the most …

Blood pressure (BP) fluctuates over 24 h, and the sympathomimetic autonomic nervous
system drives these circadian variations due to increased activity of renin-angiotensin …

Several previous studies found that too great a reduction of clinic blood pressure (BP) by
treatment increased cardiovascular disease (CVD) risk, whereas moderate reduction …

Some studies based on ambulatory blood pressure (BP) monitoring (ABPM) have reported a
reduction in sleep-time relative BP decline towards a more non-dipping pattern in the …

Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications:
Controversies in Hypertension - Con Side of the Argument | Hypertension Science Volunteer …

Clinical studies have documented morning-evening, administration-time differences of
several different classes of hypertension medications in blood pressure (BP)-lowering …