Environmental enrichment potentiates neural plasticity, enhancing acquisition and
consolidation of memory traces. In the sensory cortices, after cortical circuit maturation and …

Neural circuits display a heightened sensitivity to external stimuli during well-established
windows in early postnatal life. After the end of these critical periods, brain plasticity …

Dark rearing is known to delay the time course of the critical period for ocular dominance
plasticity in the visual cortex. Recent evidence suggests that a period of dark exposure (DE) …

The brain has a remarkable capacity to adapt to alterations in its sensory environment,
which is normally much more pronounced in juvenile animals. Here we show that in adult …

Brain aging is characterized by functional deterioration across multiple systems, associated
to a progressive decay of neural plasticity. Here, we explored environmental enrichment …

Neural circuits are shaped by experience during critical periods of development. Sensory
deprivation during these periods permanently compromises an organism's ability to perceive …

Ocular dominance (OD) plasticity in mouse primary visual cortex (V1) declines during
postnatal development and is absent beyond postnatal day 110 if mice are raised in …

Experimental evidence derived from in vitro studies suggests that synaptic plasticity may be
involved in information processing in the adult sensory cortex. Here, we demonstrate, for the …

Environmental enrichment is a model of increased structural brain plasticity. Previous
histological observations have shown molecular and cellular changes in a few pre …

The sensitivity of ocular dominance to regulation by monocular deprivation is the canonical
model of plasticity confined to a critical period. However, we have previously shown that …