Angiotensin II type 1 receptor antagonists prevent glucose‐induced increases in islet blood flow in rats

M Iwase, Y Uchizono, S Nohara, N Sasaki… - … Journal of Clinical …, 2009 - Taylor & Francis
Objective. Renin‐angiotensin system inhibitors are reported to be beneficial in delaying the
onset of diabetes mellitus. Since islet blood hyperperfusion during hyperglycaemia may be …

Effect of type-1 diabetes mellitus on the regulation of insulin and endothelin-1 receptors in rat hearts

N Nuwayri-Salti, CN Karam… - Canadian journal of …, 2007 - cdnsciencepub.com
This project assesses the treatment role with insulin and (or) angiotensin II receptor subtype-
1 (AT1-R) blocker (ARB) on insulin receptor and endothelin-1 receptor subtype (ETA-R and …

Olmesartan ameliorates peripheral nerve dysfunction in Zucker diabetic fatty rats

K Sugimoto, K Kojima, M Baba… - Journal of …, 2011 - journals.lww.com
Objective Angiotensin (ANG) II type 1 receptor (AT1R) blockers have neuroprotective effects
against neuronal lesions. The present study examines whether the AT1R blocker …

Streptozotocin-induced diabetes selectively alters the potency of analgesia produced by μ-opioid agonists, but not by δ-and κ-opioid agonists

J Kamei, Y Ohhashi, T Aoki, N Kawasima, Y Kasuya - Brain research, 1992 - Elsevier
To investigate the possible mechanisms of the alterations in morphine-induced analgesia
observed in diabetic mice, we examined the influence of streptozotocin-induced (STZ …

Loperamide increases glucose ultilization in streptozotocin‐induced diabetic rats

TF Tzeng, IM Liu, TY Lai, CC Tsai… - Clinical and …, 2003 - Wiley Online Library
Loperamide has an ability to lower the plasma glucose concentration in streptozotocin (STZ)‐
induced diabetic rats. In the present study, we investigated the molecular mechanisms by …

Role of angiotensin II type-1 and type-2 receptors on vascular smooth muscle cell growth and glucose metabolism in diabetic rats

M Igarashi, A Hirata, H Nozaki… - Diabetes research and …, 2007 - Elsevier
This study investigates the mechanisms whereby angiotensin II (Ang II) signaling contributes
to cell growth and glucose metabolism in cultured vascular smooth muscle cells (VSMCs) …

Angiotensin receptor blockade increases pancreatic insulin secretion and decreases glucose intolerance during glucose supplementation in a model of metabolic …

R Rodriguez, JA Viscarra, JN Minas, D Nakano… - …, 2012 - academic.oup.com
Renin-angiotensin system blockade improves glucose intolerance and insulin resistance,
which contribute to the development of metabolic syndrome. However, the contribution of …

The role of I1-imidazoline and α2-adrenergic receptors in the modulation of glucose metabolism in the spontaneously hypertensive obese rat model of metabolic …

RA Velliquette, P Ernsberger - Journal of Pharmacology and Experimental …, 2003 - ASPET
We examined glucose metabolism after I1-imidazoline (I1R) and α2-adrenergic receptor
(α2AR) activation in an animal model of metabolic syndrome X. Fasted spontaneously …

[HTML][HTML] Garlic (allium sativum) modulates the expression of angiotensin II AT2 receptor in adrenal and renal tissues of streptozotocin-induced diabetic rats

MH Mansour, K Al-Qattan, M Thomson, M Ali - Advances in Biological …, 2011 - scirp.org
The loss of balance between the antagonistic activities of angiotensin II AT1/AT2 receptors
has been impli-cated as a major mediator in the development of hypertension and …

Effects of angiotensin-converting enzyme inhibitors on glucose uptake

A Kudoh, A Matsuki - Hypertension, 2000 - Am Heart Assoc
We investigated the effect of angiotensin-converting enzyme inhibitors on glucose uptake
regulation as well as the effect of bradykinin (BK) on glucose uptake and its regulation by …