Antiretroviral therapy for HIV infection needs lifelong access and strict adherence to
regimens that are both expensive and associated with toxic effects. A curative intervention …

Our understanding of the pathogenesis of AIDS has advanced considerably since the
disease was first reported 15 years ago. We now know that the primary damage inflicted by …

The massive scale-up of HIV treatment and prevention over the past two decades has
resulted in important reductions in new infections and mortality globally. Reduction in HIV …

Antiretroviral therapy of HIV infection has changed a uniformly fatal into a potentially chronic
disease. There are now 17 drugs in common use for HIV treatment. Patients who can access …

In The Lancet today, Reuben Granich and colleagues (including two of us, KMDC and CFG)
use mathematical modelling to assess the impact of expanded HIV testing and earlier …

Continuing expansion of the HIV/AIDS pandemic has been recognised as an exceptional
challenge to global health, international development, and world security. UNAIDS …

Randomised, controlled trial data show that combination antiretroviral therapy for HIV-1
infection benefits people with CD4-cell counts less than 350 cells/μL. Based on currently …

The HIV-1 pandemic is a complex mix of diverse epidemics within and between countries
and regions of the world, and is undoubtedly the defining public-health crisis of our time …

Comment e810 www. thelancet. com/hiv Vol 6 December 2019 led to an increase in people
living with HIV from 8· 74 million in 1990 to 36· 82 million in 2017. Young adults remain at …

In March, 2006, the WHO took stock of the 3 by 5 initiative, which had been formally
launched with UNAIDS 2 years earlier. 1 With 1· 3 million people on antiretroviral treatment …