Many stereoselective peptide catalysts have been established. They consist, like nature's
catalysts, of amino acids but have significantly lower molecular weights than enzymes …

Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Enzymes' machinery has been an inspiration for chemists. Peptides are vital players in the
origin of life, being ancestors of complex enzymes. Even short peptides that are simple in …

Conspectus Enzymes are biogenic catalysts that enable the vital activity of organisms.
Enzymes promote reactions in a selective manner with a high level of substrate recognition …

The properties of synthetic peptides, including potency, stability, and bioavailability, are
strongly influenced by modification of the peptide chain termini. Unfortunately, generally …

Conspectus Nature's catalytic machinery has provided endless inspiration for chemists.
While the enzymatic ideal has yet to be fully realized, the field has made tremendous strides …

Folded peptides have proven to be a fertile area for discovery of catalysts for reactions in
organic synthesis. Both combinatorial chemistry and rational design have fueled these …

Highlights•Enantioselective and diastereoselective synthesis of atropoisomers.•
Stereoselective synthesis of acyclic compounds bearing all-carbon quaternary stereogenic …

Trans/cis isomerization of Xaa-Pro bonds is key for the structure and function of several
enzymes. In recent years, numerous versatile peptidic catalysts have been developed that …

The development of peptide-based enzyme mimics as organic catalysts for enantioselective
synthesis is of rapidly growing interest today. In the following a brief overview about …