Molecular mechanisms of antiproliferative effects of natural chalcones
R Michalkova, L Mirossay, M Gazdova, M Kello… - Cancers, 2021 - mdpi.com
Simple Summary Despite the important progress in cancer treatment in the past decades,
the mortality rates in some types of cancer have not significantly decreased. Therefore, the …
the mortality rates in some types of cancer have not significantly decreased. Therefore, the …
Anticancer potential of natural chalcones: in vitro and in vivo evidence
R Michalkova, L Mirossay, M Kello… - International Journal of …, 2023 - mdpi.com
There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …
decades. However, the discovery of new molecules with potential antitumor properties still …
Recent progresses in chalcone derivatives as potential anticancer agents
J Yang, J Lv, S Cheng, T Jing, T Meng… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
Chalcones against the hallmarks of cancer: A mini-review
PS de Souza, GCC Bibá, EDN Melo… - Natural Product …, 2021 - Taylor & Francis
Abstract Chalcones (1, 3-diphenylpropen-1-ones) are a class of flavonoids that have been
shown a broad spectrum of biological activities with therapeutic potential. Naturally …
shown a broad spectrum of biological activities with therapeutic potential. Naturally …
Chalcone scaffolds as anticancer drugs: a review on molecular insight in action of mechanisms and anticancer properties
Cancer is the deadliest disease worldwide and the development of safer chemical entities to
treat cancer is one of the major challenges of medicinal chemistry. The emergence of new …
treat cancer is one of the major challenges of medicinal chemistry. The emergence of new …
Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
Chalcones: Promising therapeutic agents targeting key players and signaling pathways regulating the hallmarks of cancer
AA WalyEldeen, S Sabet, HM El-Shorbagy… - Chemico-Biological …, 2023 - Elsevier
The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …
urgent due to the development of malignancies that are resistant to chemotherapeutic …
A review on mechanisms of anti tumor activity of chalcones
Chalcones comprise a characteristic framework of 1, 3-diaryl-2-propen-1-one. They have
been heralded as promising anti cancer drugs and have received much attention in the field …
been heralded as promising anti cancer drugs and have received much attention in the field …
Heterocyclic chalcone analogues as potential anticancer agents
Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
An update on antitumor activity of naturally occurring chalcones
EH Zhang, RF Wang, SZ Guo… - … Based Complementary and …, 2013 - Wiley Online Library
Chalcones, which have characteristic 1, 3‐diaryl‐2‐propen‐1‐one skeleton, are mainly
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …