Purification of a meningeal cell‐derived chondroitin sulphate proteoglycan with neurotrophic activity for brain neurons and its identification as biglycan
U Junghans, A Koops, A Westmeyer… - European Journal of …, 1995 - Wiley Online Library
Serum‐free cultures of meningeal fibroblasts synthesize and release a chondroitin sulphate
proteoglycan (CSPG) that markedly enhances survival but not adhesion of embryonic rat …
proteoglycan (CSPG) that markedly enhances survival but not adhesion of embryonic rat …
Cultured astrocytes express biglycan, a chondroitin/dermatan sulfate proteoglycan supporting the survival of neocortical neurons
A Koops, J Kappler, U Junghans, G Kuhn… - Molecular brain …, 1996 - Elsevier
Astrocyte-conditioned medium (ACM) supports the survival of rat E15 neocortical neurons.
Using a microtiter assay for neuronal survival, we demonstrated that part of the survival …
Using a microtiter assay for neuronal survival, we demonstrated that part of the survival …
Core protein of chondroitin sulfate proteoglycan promotes neurite outgrowth from cultured neocortical neurons
N Iijima, A Oohira, T Mori, K Kitabatake… - Journal of …, 1991 - Wiley Online Library
Chondroitin sulfate proteoglycan (CS‐PG) was purified from rat brain and examined for its
effect on neurite outgrowth in primary cultures of embryonic rat neocortical neurons. Neurite …
effect on neurite outgrowth in primary cultures of embryonic rat neocortical neurons. Neurite …
Large chondroitin sulfate proteoglycans of developing chick CNS are expressed in cerebral hemisphere neuronal cultures
AK Hennig, D Mangoura, NB Schwartz - Developmental brain research, 1993 - Elsevier
Chondroitin sulfate proteoglycans (CSPG) of the extracellular matrix may play regulatory
roles in central nervous system (CNS) development. We have examined the expression of …
roles in central nervous system (CNS) development. We have examined the expression of …
Inhibition and enhancement of neural regeneration by chondroitin sulfate proteoglycans
H Rauvala, M Paveliev, J Kuja-Panula… - Neural regeneration …, 2017 - journals.lww.com
The current dogma in neural regeneration research implies that chondroitin sulfate
proteoglycans (CSPGs) inhibit plasticity and regeneration in the adult central nervous …
proteoglycans (CSPGs) inhibit plasticity and regeneration in the adult central nervous …
Inhibitory effects of brain chondroitin sulfate proteoglycans on neurite outgrowth from PC12D cells
A Oohira, F Matsui, R Katoh-Semba - Journal of Neuroscience, 1991 - Soc Neuroscience
Soluble chondroitin sulfate proteoglycans (CSPGs), prepared from 10-d-old rat brain, were
added to the culture medium of PC12D cells containing NGF to examine the effects on NGF …
added to the culture medium of PC12D cells containing NGF to examine the effects on NGF …
Chondroitin sulphate proteoglycans in the rat brain: candidates for axon barriers of sensory neurons and the possible modification by laminin of their actions
R Katoh‐Semba, M Matsuda, K Kato… - European Journal of …, 1995 - Wiley Online Library
The addition of chondroitin sulphate proteoglycans (CSPGs), purified from the rat brain, to
the culture medium of PC12D cells inhibited their proliferation and neurite outgrowth …
the culture medium of PC12D cells inhibited their proliferation and neurite outgrowth …
Growth factor and cytokine regulation of chondroitin sulfate proteoglycans by astrocytes
After injury to the adult central nervous system (CNS), numerous cytokines and growth
factors are released that contribute to reactive gliosis and extracellular matrix production. In …
factors are released that contribute to reactive gliosis and extracellular matrix production. In …
Developmentally regulated expression of a brain specific species of chondroitin sulfate proteoglycan, neurocan, identified with a monoclonal antibody 1G2 in the rat …
A Oohira, F Matsui, E Watanabe, Y Kushima, N Maeda - Neuroscience, 1994 - Elsevier
The mammalian brain contains many species of proteoglycan. To identify each proteoglycan
species, we have raised monoclonal antibodies against soluble chondroitin sulfate …
species, we have raised monoclonal antibodies against soluble chondroitin sulfate …
Chondroitin sulphate proteoglycans in the central nervous system: changes and synthesis after injury
F Properzi, RA Asher, JW Fawcett - Biochemical Society …, 2003 - portlandpress.com
Chondroitin sulphate proteoglycans (CSPGs) are up-regulated in the central nervous system
after injury, specifically around the lesion site where the glial scar forms. This structure …
after injury, specifically around the lesion site where the glial scar forms. This structure …