Capturing the latent space of an Autoencoder for multi-omics integration and cancer subtyping

S Paul - Computers in Biology and Medicine, 2022 - Elsevier
Abstract Background and Objective: The motivation behind cancer subtyping is to identify
subgroups of cancer patients with distinguishable phenotypes of clinical importance. It can …

Deep structure integrative representation of multi-omics data for cancer subtyping

B Yang, Y Yang, X Su - Bioinformatics, 2022 - academic.oup.com
Motivation Cancer is a heterogeneous group of diseases. Cancer subtyping is a crucial and
critical step to diagnosis, prognosis and treatment. Since high-throughput sequencing …

Subtype-GAN: a deep learning approach for integrative cancer subtyping of multi-omics data

H Yang, R Chen, D Li, Z Wang - Bioinformatics, 2021 - academic.oup.com
Motivation The discovery of cancer subtyping can help explore cancer pathogenesis,
determine clinical actionability in treatment, and improve patients' survival rates. However …

Performance comparison of deep learning autoencoders for cancer subtype detection using multi-omics data

EF Franco, P Rana, A Cruz, VV Calderon, V Azevedo… - Cancers, 2021 - mdpi.com
Simple Summary Here, we compared the performance of four different autoencoders:(a)
vanilla,(b) sparse,(c) denoising, and (d) variational for subtype detection on four cancer …

Subtype-WESLR: identifying cancer subtype with weighted ensemble sparse latent representation of multi-view data

W Song, W Wang, DQ Dai - Briefings in Bioinformatics, 2022 - academic.oup.com
The discovery of cancer subtypes has become much-researched topic in oncology. Dividing
cancer patients into subtypes can provide personalized treatments for heterogeneous …

SADLN: Self-attention based deep learning network of integrating multi-omics data for cancer subtype recognition

Q Sun, L Cheng, A Meng, S Ge, J Chen, L Zhang… - Frontiers in …, 2023 - frontiersin.org
Integrating multi-omics data for cancer subtype recognition is an important task in
bioinformatics. Recently, deep learning has been applied to recognize the subtype of …

Subtype-DCC: decoupled contrastive clustering method for cancer subtype identification based on multi-omics data

J Zhao, B Zhao, X Song, C Lyu, W Chen… - Briefings in …, 2023 - academic.oup.com
Due to the high heterogeneity and complexity of cancers, patients with different cancer
subtypes often have distinct groups of genomic and clinical characteristics. Therefore, the …

[HTML][HTML] MOCSS: Multi-omics data clustering and cancer subtyping via shared and specific representation learning

Y Chen, Y Wen, C Xie, X Chen, S He, X Bo, Z Zhang - Iscience, 2023 - cell.com
Cancer is an extremely complex disease and each type of cancer usually has several
different subtypes. Multi-omics data can provide more comprehensive biological information …

A hierarchical integration deep flexible neural forest framework for cancer subtype classification by integrating multi-omics data

J Xu, P Wu, Y Chen, Q Meng, H Dawood, H Dawood - BMC bioinformatics, 2019 - Springer
Background Cancer subtype classification attains the great importance for accurate
diagnosis and personalized treatment of cancer. Latest developments in high-throughput …

Multi-omics clustering for cancer subtyping based on latent subspace learning

X Ye, Y Shang, T Shi, W Zhang, T Sakurai - Computers in Biology and …, 2023 - Elsevier
The increased availability of high-throughput technologies has enabled biomedical
researchers to learn about disease etiology across multiple omics layers, which shows …