Objective To determine whether topical application of insulin normalizes delayed corneal
wound healing in rats with diabetes mellitus (DB). Methods Diabetes mellitus was induced …

Patients with diabetes are at an increased risk for developing corneal disorders, often as a
result of surgical and nonsurgical trauma. This study investigated whether intensive …

BACKGROUND Diabetic keratopathy (DK) occurs in 46%-64% of patients with diabetes and
requires serious attention. In patients with diabetes, the healing of corneal epithelial defects …

Purpose: To determine the effect of topical insulin of 3 concentrations [0.5, 1, and 2 units per
drop 4 times per day (QID)] on postoperative corneal epithelial wound healing in diabetic …

Patients with diabetes are at increased risk for developing corneal disorders, termed
diabetic keratopathy. Treatments for diabetic keratopathy are limited. Preclinical studies …

Purpose.: The purpose of the study was to investigate the effects of hyperglycemia on EGFR
(epidermal growth factor receptor)-mediated wound response and signal transduction in the …

To determine whether the effect of fibronectin on corneal epithelial healing occurs in eyes
affected by diabetes, the effect of fibronectin on the rates at which corneal epithelial wounds …

Diabetic patients can develop degenerative corneal changes, termed diabetic keratopathy,
during the course of their disease. Topical insulin has been shown to reduce corneal wound …

Objective To evaluate the efficacy of insulin eye drops for dry eye disease in reducing
corneal staining and improving symptoms. Methods In this retrospective case series …

purpose. To investigate the effects of insulin and leptin on in vitro wound healing of
transformed human corneal epithelial cell monolayers and to identify cellular (migration …