Anticholinergic drugs for the treatment of COPD are safe… are they?

KF Rabe - Chest, 2010 - journal.chestnet.org
COPD is increasingly recognized as a complex systemic disorder with a whole range of
comorbidities, especially cardiovascular, contributing significantly to COPD morbidity and …

A systematic review of the cardiovascular risk of inhaled anticholinergics in patients with COPD

DE Hilleman, MA Malesker, LE Morrow… - International journal of …, 2009 - Taylor & Francis
The long-term use of inhaled anticholinergic agents has recently been suggested to be
associated with an excess risk of adverse cardiovascular (CV) outcomes in patients with …

[引用][C] inhaled anticholinergics increase risk of major cardiovascular events in COPD.

MB Stanbrook - Evidence-based Medicine, 2009 - europepmc.org
Review: inhaled anticholinergics increase risk of major cardiovascular events in COPD. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Do inhaled anticholinergics increase or decrease the risk of major cardiovascular events? A synthesis of the available evidence

SR Salpeter - Drugs, 2009 - Springer
There has been recent uncertainty about whether the inhaled anticholinergic agents
ipratropium bromide and tiotropium bromide increase or decrease cardiovascular risk in the …

Drug safety in COPD revisited: what is the number needed to analyze?

KF Rabe - Chest, 2012 - journal.chestnet.org
The treatment of COPD worldwide relies on a rather limited selection of pharmacologic
principles. Symptomatic benefit and improvement of lung function are afforded by β 2 …

Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta …

S Singh, YK Loke, CD Furberg - Jama, 2008 - jamanetwork.com
Context Inhaled anticholinergics (ipratropium bromide or tiotropium bromide) are widely
used in patients with chronic obstructive pulmonary disease (COPD) but their effect on the …

The use of inhaled anticholinergics in chronic obstructive pulmonary disease: is there cause for concern? A review of evidence from clinical trials.

A Sindi, A McIvor - Polskie Archiwum Medycyny Wewnetrznej, 2009 - europepmc.org
Chronic obstructive pulmonary disease (COPD) is a common condition affecting men and
women equally that worsens quality of life and increases mortality. The burden of illness …

Pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications

S Singh, YK Loke, P Enright, CD Furberg - Thorax, 2013 - thorax.bmj.com
The majority of deaths in COPD are from cardiovascular causes. Several large randomized
controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium …

Republished: pro-arrhythmic and pro-ischaemic effects of inhaled anticholinergic medications

S Singh, YK Loke, P Enright… - Postgraduate Medical …, 2014 - academic.oup.com
The majority of deaths in COPD are from cardiovascular causes. Several large randomized
controlled trials demonstrate that inhaled anticholinergic agents ipratropium and tiotropium …

Inhaled anticholinergics and the long-term treatment of chronic obstructive pulmonary disease: Weighing benefits and risks

DK Hogarth, TA Jacobson - Clinical Cornerstone, 2009 - Elsevier
A meta-analysis recently published in the Journal of the American Medical Association
found an increased risk of nonfatal myocardial infarction, stroke, and cardiovascular death …