Mobile elements such as Alu repeats have substantially altered the architecture of the
human genome, and de novo mobile element insertions sometimes cause genetic …

Alu elements are transposable elements that have reached over one million copies in the
human genome. Some Alu elements inserted in the genome so recently that they are still …

Abstract Background Polymorphic human Alu elements are excellent tools for assessing
population structure, and new retrotransposition events can contribute to disease. Next …

Alu elements, the short interspersed element numbering more than 1 million copies per
human genome, can mediate the formation of copy number variants (CNVs) between …

The nearly one million Alu repeats in human chromosomes are a potential threat to genome
integrity. Alus form dense clusters where they frequently appear as inverted repeats, a …

Alu elements represent the largest family of human mobile elements in copy number. A
controversial issue with implications for both Alu biology and human genome evolution is …

Alu retrotransposons are the most numerous and active mobile elements in humans,
causing genetic disease and creating genomic diversity. Mobile element scanning (ME …

Alu elements represent one of the most common sources of homology and homeology in the
human genome. Homeologous recombination between Alu elements represents a major …

Alu elements comprise> 10% of the human genome. We have used a computational biology
approach to analyze the human genomic DNA sequence databases to determine the impact …

Alu retrotransposons account for more than 10% of the human genome, and insertions of
these elements create structural variants segregating in human populations. Such …