Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability
JE Stenger, KS Lobachev, D Gordenin… - Genome …, 2001 - genome.cshlp.org
Alu sequences, the most abundant class of large dispersed DNA repeats in human
chromosomes, contribute to human genome dynamics. Recently we reported that long …
chromosomes, contribute to human genome dynamics. Recently we reported that long …
The role of recombination in the origin and evolution of Alu subfamilies
Alus are the most abundant and successful short interspersed nuclear elements found in
primate genomes. In humans, they represent about 10% of the genome, although few are …
primate genomes. In humans, they represent about 10% of the genome, although few are …
Aluinsertion polymorphisms and human evolution: Evidence for a larger population size in Africa
M Stoneking, JJ Fontius, SL Clifford… - Genome …, 1997 - genome.cshlp.org
Alu insertion polymorphisms (polymorphisms consisting of the presence/absence of an Alu
element at a particular chromosomal location) offer several advantages over other nuclear …
element at a particular chromosomal location) offer several advantages over other nuclear …
Alu repeats and human genomic diversity
MA Batzer, PL Deininger - Nature reviews genetics, 2002 - nature.com
During the past 65 million years, Alu elements have propagated to more than one million
copies in primate genomes, which has resulted in the generation of a series of Alu …
copies in primate genomes, which has resulted in the generation of a series of Alu …
Alu Recombination-Mediated Structural Deletions in the Chimpanzee Genome
With more than 1.2 million copies, Alu elements are one of the most important sources of
structural variation in primate genomes. Here, we compare the chimpanzee and human …
structural variation in primate genomes. Here, we compare the chimpanzee and human …
Differential Alu mobilization and polymorphism among the human and chimpanzee lineages
Alu elements are primate-specific members of the SINE (s hort in terspersed e lement)
retroposon family, which comprise∼ 10% of the human genome. Here we report the first …
retroposon family, which comprise∼ 10% of the human genome. Here we report the first …
Recent Insertion of an Alu Element Within a Polymorphic Human-Specific Alu Insertion
Alu elements are a family of short interspersed repeats that have mobilized throughout
primate genomes by retrotransposition over the past 65 Myr of primate evolution (for a …
primate genomes by retrotransposition over the past 65 Myr of primate evolution (for a …
Insertion and deletion polymorphisms of the ancient AluS family in the human genome
MS Kryatova, JP Steranka, KH Burns, LM Payer - Mobile DNA, 2017 - Springer
Abstract Background Polymorphic Alu elements account for 17% of structural variants in the
human genome. The majority of these belong to the youngest AluY subfamilies, and most …
human genome. The majority of these belong to the youngest AluY subfamilies, and most …
Evolutionary impact of human Alu repetitive elements
J Jurka - Current opinion in genetics & development, 2004 - Elsevier
Early studies of human Alu retrotransposons focused on their origin, evolution and biological
properties, but current focus is shifting toward the effect of Alu elements on evolution of the …
properties, but current focus is shifting toward the effect of Alu elements on evolution of the …
Comprehensive analysis of Alu-associated diversity on the human sex chromosomes
A comprehensive analysis of the human sex chromosomes was undertaken to assess Alu-
associated human genomic diversity and to identify novel Alu insertion polymorphisms for …
associated human genomic diversity and to identify novel Alu insertion polymorphisms for …