Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability

JE Stenger, KS Lobachev, D Gordenin… - Genome …, 2001 - genome.cshlp.org
Alu sequences, the most abundant class of large dispersed DNA repeats in human
chromosomes, contribute to human genome dynamics. Recently we reported that long …

The role of recombination in the origin and evolution of Alu subfamilies

A Teixeira-Silva, RM Silva, J Carneiro, A Amorim… - PloS one, 2013 - journals.plos.org
Alus are the most abundant and successful short interspersed nuclear elements found in
primate genomes. In humans, they represent about 10% of the genome, although few are …

Aluinsertion polymorphisms and human evolution: Evidence for a larger population size in Africa

M Stoneking, JJ Fontius, SL Clifford… - Genome …, 1997 - genome.cshlp.org
Alu insertion polymorphisms (polymorphisms consisting of the presence/absence of an Alu
element at a particular chromosomal location) offer several advantages over other nuclear …

Alu repeats and human genomic diversity

MA Batzer, PL Deininger - Nature reviews genetics, 2002 - nature.com
During the past 65 million years, Alu elements have propagated to more than one million
copies in primate genomes, which has resulted in the generation of a series of Alu …

Alu Recombination-Mediated Structural Deletions in the Chimpanzee Genome

K Han, J Lee, TJ Meyer, J Wang, SK Sen… - PLoS …, 2007 - journals.plos.org
With more than 1.2 million copies, Alu elements are one of the most important sources of
structural variation in primate genomes. Here, we compare the chimpanzee and human …

Differential Alu mobilization and polymorphism among the human and chimpanzee lineages

DJ Hedges, PA Callinan, R Cordaux, J Xing… - Genome …, 2004 - genome.cshlp.org
Alu elements are primate-specific members of the SINE (s hort in terspersed e lement)
retroposon family, which comprise∼ 10% of the human genome. Here we report the first …

Recent Insertion of an Alu Element Within a Polymorphic Human-Specific Alu Insertion

D Comas, S Plaza, F Calafell, A Sajantila… - Molecular Biology …, 2001 - academic.oup.com
Alu elements are a family of short interspersed repeats that have mobilized throughout
primate genomes by retrotransposition over the past 65 Myr of primate evolution (for a …

Insertion and deletion polymorphisms of the ancient AluS family in the human genome

MS Kryatova, JP Steranka, KH Burns, LM Payer - Mobile DNA, 2017 - Springer
Abstract Background Polymorphic Alu elements account for 17% of structural variants in the
human genome. The majority of these belong to the youngest AluY subfamilies, and most …

Evolutionary impact of human Alu repetitive elements

J Jurka - Current opinion in genetics & development, 2004 - Elsevier
Early studies of human Alu retrotransposons focused on their origin, evolution and biological
properties, but current focus is shifting toward the effect of Alu elements on evolution of the …

Comprehensive analysis of Alu-associated diversity on the human sex chromosomes

PA Callinan, DJ Hedges, AH Salem, J Xing, JA Walker… - Gene, 2003 - Elsevier
A comprehensive analysis of the human sex chromosomes was undertaken to assess Alu-
associated human genomic diversity and to identify novel Alu insertion polymorphisms for …