Alu insertion polymorphisms for the study of human genomic diversity

AM Roy-Engel, ML Carroll, E Vogel, RK Garber… - Genetics, 2001 - academic.oup.com
Genomic database mining has been a very useful aid in the identification and retrieval of
recently integrated Alu elements from the human genome. We analyzed Alu elements …

Whole-genome analysis of Alu repeat elements reveals complex evolutionary history

AL Price, E Eskin, PA Pevzner - Genome research, 2004 - genome.cshlp.org
Alu repeats are the most abundant family of repeats in the human genome, with over 1
million copies comprising 10% of the genome. They have been implicated in human genetic …

Evolution and distribution of RNA polymerase II regulatory sites from RNA polymerase III dependant mobile Alu elements

R Shankar, D Grover, SK Brahmachari… - BMC Evolutionary …, 2004 - Springer
Abstract Background The primate-specific Alu elements, which originated 65 million years
ago, exist in over a million copies in the human genome. These elements have been …

Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions

G Antunez‐de‐Mayolo, A Antunez‐de‐Mayolo… - …, 2002 - Wiley Online Library
Alu elements, the largest family of interspersed repeats, mobilize throughout the genomes of
primates by retroposition. Alu are present in humans in an excess of 500 000 copies per …

Regulating Alu element 'exonization'

H Stower - Nature Reviews Genetics, 2013 - nature.com
Alu elements are the most abundant transposable elements in the human genome. They
contain characteristic cryptic splice sites that are used under rare circumstances, such that …

Alu distribution and mutation types of cancer genes

W Zhang, A Edwards, W Fan, P Deininger, K Zhang - BMC genomics, 2011 - Springer
Background Alu elements are the most abundant retrotransposable elements comprising~
11% of the human genome. Many studies have highlighted the role that Alu elements have …

Polymorphic Alu insertions in six Brazilian African‐derived populations

NH Cotrim, MTBM Auricchio, JP Vicente… - American Journal of …, 2004 - Wiley Online Library
At least 25 African‐derived populations (quilombo remnants) are believed to exist in the
Ribeira River Valley, located in the southern part of São Paulo State, Brazil. We studied four …

Retrotransposition of Alu elements: how many sources?

R Cordaux, DJ Hedges, MA Batzer - TRENDS in genetics, 2004 - cell.com
It is generally thought that only a few Alu elements are capable of retrotransposition and that
these 'master'sources produce inactive copies. Here, we use a network phylogenetic …

Detecting Alu insertions from high-throughput sequencing data

M David, H Mustafa, M Brudno - Nucleic acids research, 2013 - academic.oup.com
High-throughput sequencing technologies have allowed for the cataloguing of variation in
personal human genomes. In this manuscript, we present alu-detect, a tool that combines …

L1 recombination-associated deletions generate human genomic variation

K Han, J Lee, TJ Meyer, P Remedios… - Proceedings of the …, 2008 - National Acad Sciences
Mobile elements have created structural variation in the human genome through their de
novo insertions and post-insertional genomic rearrangements. L1 elements are a type of …