DNA methylation variation of human-specific Alu repeats
ABSTRACT DNA methylation is the major repression mechanism for human
retrotransposons, such as the Alu family. Here, we have determined the methylation levels …
retrotransposons, such as the Alu family. Here, we have determined the methylation levels …
Insights on human evolution: an analysis of Alu insertion polymorphisms
MC Terreros, MA Alfonso-Sánchez, GE Novick… - Journal of human …, 2009 - nature.com
We analyzed the genetic profile of 563 individuals from 12 geographically targeted human
populations from Europe, Asia and Africa using 27 human-specific polymorphic Alu …
populations from Europe, Asia and Africa using 27 human-specific polymorphic Alu …
Alu exaptation enriches the human transcriptome by introducing new gene ends
E Lavi, L Carmel - RNA biology, 2018 - Taylor & Francis
In mammals, transposable elements are largely silenced, but under fortuitous circumstances
may be co-opted to play a functional role. Here, we show that when Alu elements are …
may be co-opted to play a functional role. Here, we show that when Alu elements are …
Shuffling of genes within low-copy repeats on 22q11 (LCR22) by Alu-mediated recombination events during evolution
M Babcock, A Pavlicek, E Spiteri, CD Kashork… - Genome …, 2003 - genome.cshlp.org
Low-copy repeats, or segmental duplications, are highly dynamic regions in the genome.
The low-copy repeats on chromosome 22q11. 2 (LCR22) are a complex mosaic of genes …
The low-copy repeats on chromosome 22q11. 2 (LCR22) are a complex mosaic of genes …
Mobile elements create structural variation: analysis of a complete human genome
Structural variants (SVs) are common in the human genome. Because approximately half of
the human genome consists of repetitive, transposable DNA sequences, it is plausible that …
the human genome consists of repetitive, transposable DNA sequences, it is plausible that …
Effects of Alu insertions on gene function
MN Szmulewicz, GE Novick, RJ Herrera - Electrophoresis, 1998 - Wiley Online Library
Alu elements are a family of short interspersed repetitive elements (SINEs) found exclusively
in primates. These elements are around 300 base pairs long, are found in excess of one …
in primates. These elements are around 300 base pairs long, are found in excess of one …
Polymorphic Alu insertions and the Asian origin of Native American populations
A rapid PCR-based assay was used to study the distribution of 5 polymorphic Alu insertions
in 895 unrelated individuals from 30 populations, 24 from North, Central, and South …
in 895 unrelated individuals from 30 populations, 24 from North, Central, and South …
Amplification dynamics of human-specific (HS) Alu family members
MA Batzer, VA Gudi, JC Mena, DW Foltz… - Nucleic acids …, 1991 - academic.oup.com
We have investigated the distribution of several recently Inserted Alu family members within
representatives of diverse human groups. Human population studies using 65 unrelated …
representatives of diverse human groups. Human population studies using 65 unrelated …
Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity
ML Carroll, AM Roy-Engel, SV Nguyen… - Journal of molecular …, 2001 - Elsevier
We have utilized computational biology to screen GenBank for the presence of recently
integrated Ya5 and Yb8 Alu family members. Our analysis identified 2640 Ya5 Alu family …
integrated Ya5 and Yb8 Alu family members. Our analysis identified 2640 Ya5 Alu family …
PAIR: polymorphic Alu insertion recognition
JI Sveinbjörnsson, BV Halldórsson - BMC bioinformatics, 2012 - Springer
Background Alu polymorphisms are some of the most common polymorphisms in the
genome, yet few methods have been developed for their detection. Methods We present …
genome, yet few methods have been developed for their detection. Methods We present …