Clinical significance of serum S100 calcium‐binding protein A4 in idiopathic pulmonary fibrosis
N Akiyama, H Hozumi, T Isayama, J Okada… - …, 2020 - Wiley Online Library
Background and objective Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial
lung disease with a poor prognosis. There are no established serum biomarkers for …
lung disease with a poor prognosis. There are no established serum biomarkers for …
[HTML][HTML] The S100 calcium-binding protein A4 level is elevated in the lungs of patients with idiopathic pulmonary fibrosis
JU Lee, HS Chang, EY Shim, JS Park, ES Koh… - Respiratory …, 2020 - Elsevier
Background Fibroblast dysfunction is the main pathogenic mechanism of idiopathic
pulmonary fibrosis (IPF). S100 calcium-binding protein A4 (S100A4) plays critical roles in …
pulmonary fibrosis (IPF). S100 calcium-binding protein A4 (S100A4) plays critical roles in …
Prognostic significance of peripheral blood S100A12, S100A8, and S100A9 concentrations in idiopathic pulmonary fibrosis
D Ding, R Luan, Q Xue, J Yang - Cytokine, 2023 - Elsevier
Abstract Background S100A12, S100A8, and S100A9 are inflammatory disease biomarkers
whose functional significance in idiopathic pulmonary fibrosis (IPF) remains unclear. We …
whose functional significance in idiopathic pulmonary fibrosis (IPF) remains unclear. We …
[HTML][HTML] S100A9 in BALF is a candidate biomarker of idiopathic pulmonary fibrosis
A Hara, N Sakamoto, Y Ishimatsu, T Kakugawa… - Respiratory …, 2012 - Elsevier
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic, progressive
fibrosing interstitial pneumonia of unknown cause, and the prognosis remains poor. On the …
fibrosing interstitial pneumonia of unknown cause, and the prognosis remains poor. On the …
Serum S100A8 and S100A9 as prognostic biomarkers in acute exacerbation of idiopathic pulmonary fibrosis
K Tanaka, N Enomoto, H Hozumi, T Isayama… - Respiratory …, 2021 - Elsevier
Background Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a devastating
and life-threatening condition during its clinical course. Biomarkers for precisely anticipating …
and life-threatening condition during its clinical course. Biomarkers for precisely anticipating …
[HTML][HTML] S100A12 as biomarker of disease severity and prognosis in patients with idiopathic pulmonary fibrosis
Y Li, Y He, S Chen, Q Wang, Y Yang, D Shen… - Frontiers in …, 2022 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is one of interstitial lung diseases (ILDs) with
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …
[HTML][HTML] S100A4+ Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts
Y Li, J Bao, Y Bian, U Erben, P Wang, K Song… - Frontiers in …, 2018 - frontiersin.org
S100A4, a calcium-binding protein, can promote pulmonary fibrosis via fibroblast activation.
Due partly to its various cellular origins, the exact role of S100A4 in the development of lung …
Due partly to its various cellular origins, the exact role of S100A4 in the development of lung …
[HTML][HTML] An atypical pulmonary fibrosis is associated with co-inheritance of mutations in the calcium binding protein genes S100A3 and S100A13
EA Al-Mutairy, FA Imtiaz, M Khalid… - European …, 2019 - Eur Respiratory Soc
Background Pulmonary fibrosis is one of the leading indications for lung transplantation. The
disease, which is of unknown aetiology, can be progressive, resulting in distortion of the …
disease, which is of unknown aetiology, can be progressive, resulting in distortion of the …
S100A9 promotes human lung fibroblast cells activation through receptor for advanced glycation end-product-mediated extracellular-regulated kinase 1/2, mitogen …
X Xu, H Chen, X Zhu, Y Ma, Q Liu, Y Xue… - Clinical & …, 2013 - academic.oup.com
S100A9 belongs to the S100 family of calcium-binding proteins and plays a key role in many
inflammatory conditions. Recent studies have found that S100A9 was elevated significantly …
inflammatory conditions. Recent studies have found that S100A9 was elevated significantly …
The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis
K Araki, R Kinoshita, N Tomonobu, Y Gohara… - Journal of Molecular …, 2021 - Springer
In patients with interstitial pneumonia, pulmonary fibrosis is an irreversible condition that can
cause respiratory failure. Novel treatments for pulmonary fibrosis are necessary …
cause respiratory failure. Novel treatments for pulmonary fibrosis are necessary …