[HTML][HTML] More autopsy studies are needed to understand the pathogenesis of severe COVID-19
SP Layne, KA Walters, JC Kash, JK Taubenberger - Nature medicine, 2022 - nature.com
To the Editor—Since SARS-CoV-2 began spreading in late 2019, a total of 379 million cases
and 5.7 million deaths have been reported so far, with the case-fatality rate of COVID-19 …
and 5.7 million deaths have been reported so far, with the case-fatality rate of COVID-19 …
[HTML][HTML] Causation or confounding: why controls are critical for characterizing long COVID
Z Amin-Chowdhury, SN Ladhani - Nature Medicine, 2021 - nature.com
To the Editor—Early reports of persisting symptoms following COVID-19 signaled a
debilitating long-term fate for an undetermined proportion of people who survive COVID …
debilitating long-term fate for an undetermined proportion of people who survive COVID …
[HTML][HTML] Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19
I Thevarajan, THO Nguyen, M Koutsakos, J Druce… - Nature medicine, 2020 - nature.com
To the Editor—We report the kinetics of immune responses in relation to clinical and
virological features of a patient with mild-to-moderate coronavirus disease 2019 (COVID-19) …
virological features of a patient with mild-to-moderate coronavirus disease 2019 (COVID-19) …
[HTML][HTML] Studying severe long COVID to understand post-infectious disorders beyond COVID-19
To the Editor—As the COVID Human Genetic Effort consortium (https://www. covidhge.
com/), we have studied genetic and immunological determinants of life-threatening COVID …
com/), we have studied genetic and immunological determinants of life-threatening COVID …
[HTML][HTML] A molecular single-cell lung atlas of lethal COVID-19
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2
infection,, but the host response at the lung tissue level is poorly understood. Here we …
infection,, but the host response at the lung tissue level is poorly understood. Here we …
[HTML][HTML] A framework for identifying regional outbreak and spread of COVID-19 from one-minute population-wide surveys
To the Editor—In December 2019, a novel coronavirus was isolated, after a cluster of
patients in China were diagnosed with pneumonia of unknown cause1. This new isolate …
patients in China were diagnosed with pneumonia of unknown cause1. This new isolate …
[HTML][HTML] Has SARS-CoV-2 reached peak fitness?
To the Editor—For the first time in the history of medicine, the evolution of a virus can be
observed 'as it happens'. Throughout this, molecular tools of unprecedented accuracy are …
observed 'as it happens'. Throughout this, molecular tools of unprecedented accuracy are …
[HTML][HTML] SARS-CoV-2 infection and persistence in the human body and brain at autopsy
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] Sampling the host response to SARS-CoV-2 in hospitals under siege
AW Charney, NW Simons, K Mouskas, L Lepow… - Nature Medicine, 2020 - nature.com
To the Editor—Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the
resulting coronavirus disease 2019 (COVID-19) have stretched healthcare systems thin …
resulting coronavirus disease 2019 (COVID-19) have stretched healthcare systems thin …
[HTML][HTML] The spatio-temporal landscape of lung pathology in SARS-CoV-2 infection
Recent studies have provided insights into the pathology of and immune response to COVID-
19 [1, 2, 3, 4, 5, 6, 7, 8]. However, a thorough investigation of the interplay between infected …
19 [1, 2, 3, 4, 5, 6, 7, 8]. However, a thorough investigation of the interplay between infected …