Growing evidence suggests that a compromised serotonergic system plays an important role
in the pathophysiology of Alzheimer's disease (AD). We assessed the expression of 5-HT …

Previous studies have implicated brain serotonin 5-HT1A receptors in several CNS
functions, including cognition, mood and emotional states. In Alzheimer disease (AD) …

The 5-HT1A receptor has been extensively studied over the last two decades. There is a
plethora of information describing its anatomical, physiological and biochemical roles in the …

Rationale Previous studies have demonstrated reductions of serotonin 5-HT 2A receptors in
the neocortex of Alzheimer's disease (AD) patients. However, it is unclear whether such …

We studied the hypothesis that disturbances in 5-HT6 receptor function in the temporal
cortex may contribute to clinical symptoms of Alzheimer's disease (AD). 5-HT6 density and 5 …

Background It has been hypothesized that alterations of the serotonergic system contribute
to neuropsychiatric symptoms in Alzheimer disease (AD). Cellular expressions of the two …

Rationale Previous studies have shown extensive serotonergic deficits in the hippocampus
of Alzheimer's disease (AD) patients. However, it is unclear whether such deficits play a role …

Even though the involvement of serotonin (5-hydroxytryptamine; 5-HT) and its receptors in
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …

Alzheimer's disease (AD) is the most common cause of dementia in elderly people. Because
of the lack of effective treatments for this illness, research focused on identifying compounds …

Alzheimer's disease (AD) is a devastating neurological condition characterized by a
progressive decline in cognitive performance accompanied by behavioral and psychological …