Impact of inappropriate empiric antimicrobial therapy on mortality of septic patients with bacteremia: a retrospective study

S Lueangarun, A Leelarasamee - … Perspectives on Infectious …, 2012 - Wiley Online Library
Background. Inappropriate empiric antimicrobials could be a major cause of unfavorable
mortality rates in co‐morbid patients. This study aimed to assess the prevalence and impact …

Inappropriate antibiotic therapy in Gram-negative sepsis increases hospital length of stay

AF Shorr, ST Micek, EC Welch, JA Doherty… - Critical care …, 2011 - journals.lww.com
Objectives: To describe the impact of initially inappropriate antibiotic therapy on hospital
length of stay in Gram-negative severe sepsis and septic shock. Design: Retrospective …

Sepsis in standard care: patients' characteristics, effectiveness of antimicrobial therapy and patient outcome—a cohort study

F Ratzinger, K Eichbichler, M Schuardt, I Tsirkinidou… - Infection, 2015 - Springer
Purpose Fast diagnosis and initiation of appropriate antibiotic therapy is pivotal for the
survival of sepsis patients. However, most studies on suspected sepsis patients are …

Association between appropriate empiric antimicrobial therapy and mortality from bloodstream infections in the intensive care unit

S Yamaga, N Shime - Journal of Infection and Chemotherapy, 2018 - Elsevier
Background Empirical antimicrobial treatment for patients presenting with bloodstream
infections is considered to affect patients' outcome. Method We conducted a single-center …

[HTML][HTML] The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit

R Zaragoza, A Artero, JJ Camarena, S Sancho… - Clinical microbiology …, 2003 - Elsevier
Objective To determine the occurrence of inadequate antimicrobial therapy among critically
ill patients with bacteremia and the factors associated with it, to identify the microorganisms …

A systematic review of the methods used to assess the association between appropriate antibiotic therapy and mortality in bacteremic patients

JC McGregor, SE Rich, AD Harris… - Clinical Infectious …, 2007 - academic.oup.com
Studies of the association between inappropriate antibiotic therapy and mortality among
bacteremic patients have generated conflicting findings. We systematically reviewed these …

Delay in antibiotic administration is associated with mortality among septic shock patients with Staphylococcus aureus bacteremia

KA Corl, F Zeba, AR Caffrey, M Hermenau… - Critical Care …, 2020 - journals.lww.com
Objectives: The relationship between the timing of antibiotics and mortality among septic
shock patients has not been examined among patients specifically with Staphylococcus …

[HTML][HTML] Timing of antibiotics in septic patients: a prospective cohort study

H Seok, J Song, JH Jeon, HK Choi, WS Choi… - Clinical Microbiology …, 2020 - Elsevier
Objectives To evaluate the effect of timing and appropriateness of antibiotics administration
on mortality in patients diagnosed with sepsis according to the Sepsis-3 definition. Methods …

Impact of inappropriate empirical antibiotic therapy on outcome of bacteremic adults visiting the ED

CC Lee, CH Lee, MC Chuang, MY Hong… - The American journal of …, 2012 - Elsevier
OBJECTIVES: To investigate the clinical impact of inappropriate empirical antibiotics on
patient outcome and determine the risk factors for mortality in bacteremic adults who visited …

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial

N Daneman, AH Rishu, W Xiong, SM Bagshaw… - Trials, 2015 - Springer
Background Bacteremia is a leading cause of mortality and morbidity in critically ill adults.
No previous randomized controlled trials have directly compared shorter versus longer …