Hydrogels as scaffolds and delivery systems to enhance axonal regeneration after injuries

OA Carballo-Molina, I Velasco - Frontiers in cellular neuroscience, 2015 - frontiersin.org
Damage caused to neural tissue by disease or injury frequently produces a discontinuity in
the nervous system (NS). Such damage generates diverse alterations that are commonly …

Hydrogels for neuroprotection and functional rewiring: a new era for brain engineering

R Fernández-Serra, R Gallego, P Lozano… - Neural Regeneration …, 2020 - journals.lww.com
The neurological devastation of neurodegenerative and cerebrovascular diseases
reinforces our perseverance to find advanced treatments to deal with these fatal pathologies …

[HTML][HTML] Progress toward finding the perfect match: Hydrogels for treatment of central nervous system injury

N Hlavac, M Kasper, CE Schmidt - Materials Today Advances, 2020 - Elsevier
Injury to the central nervous system remains a significant therapeutic challenge from a tissue
engineering perspective because of the soft tissue properties, anatomical and spatial …

Injectable uncrosslinked biomimetic hydrogels as candidate scaffolds for neural stem cell delivery

K Farrell, J Joshi, CR Kothapalli - Journal of Biomedical …, 2017 - Wiley Online Library
Mammalian central nervous system has a limited ability for self‐repair under diseased or
injury conditions. Repair strategies focused on exogenously delivering autologous neural …

Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement

PH Lin, Q Dong, SY Chew - Materials Advances, 2021 - pubs.rsc.org
Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …

Recent trends in the development of peptide and protein-based hydrogel therapeutics for the healing of CNS injury

N Mukherjee, A Adak, S Ghosh - Soft Matter, 2020 - pubs.rsc.org
Traumatic brain injury (TBI) and spinal cord injury (SCI) cause millions of deaths and
permanent or prolonged physical disabilities around the globe every year. It generally …

[HTML][HTML] Engineered hydrogels for peripheral nerve repair

Y Liu, X Zhang, C Xiao, B Liu - Materials Today Bio, 2023 - Elsevier
Peripheral nerve injury (PNI) is a complex disease that often appears in young adults. It is
characterized by a high incidence, limited treatment options, and poor clinical outcomes …

Self-healing hydrogel for tissue repair in the central nervous system

FY Hsieh, TC Tseng, S Hsu - Neural regeneration research, 2015 - journals.lww.com
Neurological disorders are diseases of the central and peripheral nervous systems. These
disorders include Alzheimer's disease, epilepsy, brain tumor, and cerebrovascular diseases …

Injectable hydrogels as novel materials for central nervous system regeneration

B Niemczyk, P Sajkiewicz… - Journal of neural …, 2018 - iopscience.iop.org
Abstract Approach. Injuries of the central nervous system (CNS) can cause serious and
permanent disability due to limited regeneration ability of the CNS. Presently available …

[HTML][HTML] Advanced biomaterials for repairing the nervous system: what can hydrogels do for the brain?

ZZ Khaing, RC Thomas, SA Geissler, CE Schmidt - Materials Today, 2014 - Elsevier
Newly developed hydrogels are likely to play significant roles in future therapeutic strategies
for the nervous system. In this review, unique features of the central nervous system (ie, the …