From reactive species to disease development: Effect of oxidants and antioxidants on the cellular biomarkers

CM Curieses Andrés… - … of Biochemical and …, 2023 - Wiley Online Library
The influence of modern lifestyle, diet, exposure to chemicals such as phytosanitary
substances, together with sedentary lifestyles and lack of exercise play an important role in …

Oxidative stress: Concept and some practical aspects

H Sies - Antioxidants, 2020 - mdpi.com
Oxidative stress is defined as “an imbalance between oxidants and antioxidants in favor of
the oxidants, leading to a disruption of redox signaling and control and/or molecular …

Oxidative stress in biological systems and its relation with pathophysiological functions: the effect of physical activity on cellular redox homeostasis

J Kruk, HY Aboul-Enein, A Kładna… - Free radical …, 2019 - Taylor & Francis
The body of evidence from the past three decades demonstrates that oxidative stress can be
involved in several diseases. This study aims to summarise the current state of knowledge …

Free radicals: relationship to human diseases and potential therapeutic applications

BL Zaric, MT Macvanin, ER Isenovic - The International Journal of …, 2023 - Elsevier
Reactive species are highly-reactive enzymatically, or non-enzymatically produced
compounds with important roles in physiological and pathophysiological cellular processes …

[HTML][HTML] Oxidative stress and human health

T Rahman, I Hosen, MMT Islam… - Advances in bioscience …, 2012 - scirp.org
Redox degenerative reactions of the biological system inevitably produce reactive oxygen
species (ROS) and their derivatives. Oxidative stress is the result of an imbalance in pro …

The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies

CA Juan, JM Pérez de la Lastra, FJ Plou… - International journal of …, 2021 - mdpi.com
Living species are continuously subjected to all extrinsic forms of reactive oxidants and
others that are produced endogenously. There is extensive literature on the generation and …

Oxidative stress and antioxidants in health and disease

TR Kıran, O Otlu, AB Karabulut - Journal of Laboratory Medicine, 2023 - degruyter.com
The increase in the formation of reactive oxygen and reactive nitrogen species of
endogenous or exogenous origin causes oxidative stress due to pro-oxidant and antioxidant …

[图书][B] Free Radicals in Human Health and

V Rani, UCS Yadav - 2015 - Springer
collaborative effort to combine approaches and ideas from different experts working on
oxidative stress. The advent of oxidative hypothesis of pathogenesis led to a paradigm shift …

Does redox regulation of cell function explain why antioxidants perform so poorly as therapeutic agents?

JMC Gutteridge - Redox report, 1999 - Taylor & Francis
In normal health, there is a balance between the formation of oxidising chemical species
and their effective removal by protective antioxidants. Antioxidants are a diverse group of …

Targeting tissue oxidative damage by means of cell signaling modulators: the antioxidant concept revisited

G Leonarduzzi, B Sottero, G Poli - Pharmacology & therapeutics, 2010 - Elsevier
The complex system of molecular communications underlying cell biochemistry and function
includes numerous components, kinases, phosphatases and transcription factors, that have …