Background: The protein AXIN2 is involved in the negative feedback regulation of the Wnt/β-
catenin signaling pathway; it functions by promoting β-catenin degradation. AXIN2 mutations …

Background: The association of genetic polymorphisms at Axis inhibition protein 2 (AXIN2)
gene and susceptibility to different cancer has attracted much interest. The present study …

Axin2 is involved in the regulation of Wnt/β-catenin pathway and implicated in cancer
development and progression. The association between AXIN2 rs2240308 polymorphism …

Background Numerous studies have reported the correlation between AXIN2 polymorphism
and cancer risk, but the results seem not consistent. In order to get an overall, accurate and …

Plenty of epidemiological studies have assessed the effects of AXIN2 polymorphisms on the
risk of developing cancer, but the available results were somewhat inconclusive. Odds ratios …

Background: The Wnt/β-catenin signaling pathway is an important regulator of cellular
functions suchas proliferation, survival and cell adhesion. Wnt/β-catenin signaling is …

Background Variants in the axis inhibition 2 (AXIN2) gene might alter the protein's structure
or function or create a multiprotein destruction complex in the Wnt signaling pathway and …

Aim: The study was aimed to explore the association between AXIN1 gene polymorphism
and epithelial ovarian cancer (EOC) susceptibility as well as prognosis. Methods: A total of …

Background Many epidemiological studies have investigated association of AXIN2 variants
on overall cancer risks; however, the available results remain inconsistent. Methods An …

Abstract Axis inhibition protein 2 (Axin2) is a negative regulator of the canonical Wnt/β-
catenin signaling pathway, and functions as a tumor suppressor in a number of human …