Long-term lacosamide retention—Real-world experience at a tertiary epilepsy center in Ireland

RN McGinty, DJ Costello - Epilepsy & Behavior, 2017 - Elsevier
Purpose To estimate the rate of long-term lacosamide retention among a real-world group of
patients at a tertiary epilepsy center in Ireland. Methods One-hundred adults first prescribed …

[HTML][HTML] Clinical experience with oral lacosamide as adjunctive therapy in adult patients with uncontrolled epilepsy: a multicentre study in epilepsy clinics in the United …

L Flores, S Kemp, K Colbeck, N Moran, J Quirk… - Seizure, 2012 - Elsevier
INTRODUCTION: Lacosamide (LCS) is a new antiepileptic drug (AED) licensed in the
European Union (EU) and United States (US) in 2008. AIMS: To evaluate the efficacy and …

Long-term retention of lacosamide in a large cohort of people with medically refractory epilepsy: a single centre evaluation

J Novy, E Bartolini, GS Bell, JS Duncan, JW Sander - Epilepsy research, 2013 - Elsevier
Lacosamide (LCM) is a recently licensed antiepileptic drug available in the UK since 2008. It
is thought to act through modulation of sodium channel slow inactivation. Its efficacy and …

Real world experience with lacosamide monotherapy-a single center 1-year follow-up study

E Maloney, RN McGinty, DJ Costello - Epilepsy Research, 2018 - Elsevier
Purpose Reporting of 'real-world'data on efficacy and tolerability of antiepileptic medications
helps to inform physicians on how newer medications perform in the clinical setting, outside …

[HTML][HTML] The retention of lacosamide in patients with epilepsy and intellectual disability in three specialised institutions

J Brenner, HJM Majoie, S van Beek, JA Carpay - Seizure, 2017 - Elsevier
Purpose We describe the effectiveness of lacosamide as adjunctive therapy in patients with
epilepsy and an intellectual disability. This information is relevant, as few data exist …

Adjunctive lacosamide—5 years' clinical experience

LJ Stephen, K Kelly, P Parker, MJ Brodie - Epilepsy research, 2014 - Elsevier
Summary Purpose In 2008, lacosamide (LCM) was licensed in Europe for the adjunctive
treatment of focal-onset seizures. At that time a prospective audit was initiated at the Western …

Lacosamide as first add-on or conversion monotherapy: A retrospective real-life study

S Casciato, PP Quarato, A Gialluisi, A D'Aniello… - Epilepsy & Behavior, 2021 - Elsevier
Abstract Purpose Lacosamide (LCM), the R-enantiomer of 2-acetamido-N-benzyl-3-
methoxypropionamide, is a newer approved antiseizure medication characterized by a …

Adjunctive lacosamide for focal epilepsy: an open‐label trial evaluating the impact of flexible titration and dosing on safety and seizure outcomes

M Baulac, S Coulbaut, P Doty, C McShea… - Epileptic …, 2017 - Wiley Online Library
Aims. To evaluate the safety and effectiveness of lacosamide in a real‐life setting with the
use of a flexible dose titration schedule and individualised maintenance doses up to the …

A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial‐onset seizures in daily …

U Runge, S Arnold, C Brandt, F Reinhardt, F Kühn… - …, 2015 - Wiley Online Library
Objective Evidence for the efficacy and safety of adjunctive lacosamide in the treatment of
partial‐onset seizures (POS) was gained during placebo‐controlled clinical trials in patients …

Safety, tolerability and pharmacokinetics of intravenous lacosamide as replacement for oral lacosamide in subjects with partial seizures

V Biton, W Rosenfeld, R Mameniškienė… - … : meeting abstracts from …, 2005 - lsmu.lt
Purpose: Investigate the safety and tolerability of intravenous lacosamide (LCM) as
replacement for oral LCM in subjects with partial-onset seizures. Methods: 60 subjects …