The synthesis, characterization, and kinetic study of two linear pentapeptides l-threonyl-l-
alanyl-l-seryl-l-histidyl-l-aspartic acid (TASHD) and l-seryl-γ-aminobutyryl-l-histidyl-γ …

Efficient hydrolysis of amide bonds has long been a reaction of interest for organic chemists.
The rate constants of proteases are unmatched by those of any synthetic catalyst. It has …

A series of novel synthetic peptides, containing a C-terminal β-amino alcohol linked to p-
methoxybenzoic acid via an ester linkage, have been prepared and tested as inhibitors …

was treated with/S-benzyl-L-aspartate9 in tetrahydro-furan-aqueous sodium hydroxide at pH
7-8 to give N-formylglycyl-^-benzyl-L-aspartate (III), mp 170,[a] D+ 6.7. NT rifluoroacetyl-O …

Serine Proteinases Mimics: Hydrolytic Activity of Cyclic Peptides Which Include a Non-natural
Amino Acid t Page 1 Tvrrnhrdrorl Lerreu, Vol. 36, No. 49. pp X987-8990, 1995 Elsevier Scmm …

The occurrence of a single reactive serine residue in several proteolytic enzymes has
indicated that the peptide sequences containing this reactiveserine are close to, or at, the …

Revised Manuscript Received February 4, 1994® abstract: The S'subsite specificity of four
homologous serine proteases, rat chymotrypsin, rat trypsin,-lytic protease, and cercarial …

Initial rates of peptide‐bond synthesis catalyzed by poly (ethylene glycol)‐modified
chymotrypsin in benzene were determined using high‐performance liquid chromatography …

The pentapeptide, Thr-Ala-Cys-His-Asp, has been synthesised by use of S-diphenylmethyl-
protected cysteine. The catalytic activity towards p-nitrophenyl acetate was comparable with …

An N‐hydroxylated peptide bond was found to be cleaved faster by an endopeptidase than
the corresponding peptide bond. This preferred enzymatic cleavage was detected during …