Real-world effectiveness of long-acting injectable antipsychotic treatments in a nationwide cohort of 12,373 patients with schizophrenia-spectrum disorders
L Boyer, B Falissard, P Nuss, C Collin, S Duret… - Molecular …, 2023 - nature.com
This mirror-image study aimed to evaluate the real-life effectiveness of long-acting injectable
antipsychotics (LAI) in schizophrenia. Patients with schizophrenia initiating LAIs January …
antipsychotics (LAI) in schizophrenia. Patients with schizophrenia initiating LAIs January …
Oral versus depot antipsychotic drugs for schizophrenia—a critical systematic review and meta-analysis of randomised long-term trials
C Leucht, S Heres, JM Kane, W Kissling, JM Davis… - Schizophrenia …, 2011 - Elsevier
OBJECTIVE: Non-adherence is a major problem in the treatment of schizophrenia. Depot
antipsychotic drugs are thought to reduce relapse rates by improving adherence, but a …
antipsychotic drugs are thought to reduce relapse rates by improving adherence, but a …
[HTML][HTML] Assessing the comparative effectiveness of long-acting injectable vs. oral antipsychotic medications in the prevention of relapse provides a case study in …
JM Kane, T Kishimoto, CU Correll - Journal of clinical epidemiology, 2013 - Elsevier
Objective As psychopathology and social functioning can worsen with repeated psychotic
episodes in schizophrenia, relapse prevention is critical. Because high nonadherence rates …
episodes in schizophrenia, relapse prevention is critical. Because high nonadherence rates …
Oral versus long‐acting injectable antipsychotics in the treatment of schizophrenia and special populations at risk for treatment nonadherence: A systematic review
S Zhornitsky, E Stip - Schizophrenia research and treatment, 2012 - Wiley Online Library
Long‐acting injectable antipsychotics (LAIs) should offer better efficacy and tolerability,
compared to oral antipsychotics due to improved adherence and more stable …
compared to oral antipsychotics due to improved adherence and more stable …
Clinical guideline recommendations for antipsychotic long-acting injections
JM Kane, C Garcia-Ribera - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundLong-acting injections (LAIs) of antipsychotic drugs were developed over 40
years ago in an attempt to improve the long-term treatment of schizophrenia. AimsTo review …
years ago in an attempt to improve the long-term treatment of schizophrenia. AimsTo review …
Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis
S Leucht, M Tardy, K Komossa, S Heres, W Kissling… - The Lancet, 2012 - thelancet.com
Background Relapse prevention with antipsychotic drugs compared with placebo in patients
with schizophrenia has not been sufficiently addressed by previous systematic reviews. We …
with schizophrenia has not been sufficiently addressed by previous systematic reviews. We …
Oral and long‐acting antipsychotics for relapse prevention in schizophrenia‐spectrum disorders: a network meta‐analysis of 92 randomized trials including 22,645 …
G Ostuzzi, F Bertolini, F Tedeschi, G Vita… - World …, 2022 - Wiley Online Library
According to current evidence and guidelines, continued antipsychotic treatment is key for
preventing relapse in people with schizophrenia‐spectrum disorders, but evidence‐based …
preventing relapse in people with schizophrenia‐spectrum disorders, but evidence‐based …
Comparison of SGA oral medications and a long-acting injectable SGA: the PROACTIVE study
PF Buckley, NR Schooler, DC Goff, J Hsiao… - Schizophrenia …, 2015 - academic.oup.com
Until relatively recently, long-acting injectable (LAI) formulations were only available for first-
generation antipsychotics and their utilization decreased as use of oral second-generation …
generation antipsychotics and their utilization decreased as use of oral second-generation …
Antipsychotics in adults with schizophrenia: comparative effectiveness of first-generation versus second-generation medications: a systematic review and meta …
L Hartling, AM Abou-Setta, S Dursun… - Annals of internal …, 2012 - acpjournals.org
Background: Debate continues about the comparative benefits and harms of first-generation
antipsychotics (FGAs) and second-generation antipsychotics (SGAs) in treating …
antipsychotics (FGAs) and second-generation antipsychotics (SGAs) in treating …
Safety and tolerability of long-acting injectable versus oral antipsychotics: a meta-analysis of randomized controlled studies comparing the same antipsychotics
F Misawa, T Kishimoto, K Hagi, JM Kane… - Schizophrenia …, 2016 - Elsevier
Objective We aimed to assess whether long-acting injectable antipsychotics (LAIs), which
are initiated in a loading strategy or overlapping with oral antipsychotics (OAPs) and which …
are initiated in a loading strategy or overlapping with oral antipsychotics (OAPs) and which …