Activation of PI3K/Akt pathway limits JNK-mediated apoptosis during EV71 infection
H Zhang, F Li, Z Pan, Z Wu, Y Wang, Y Cui - Virus research, 2014 - Elsevier
Apoptosis is frequently induced to inhibit virus replication during infection of Enterovirus 71
(EV71). On the contrary, anti-apoptotic pathway, such as PI3K/Akt pathway, is …
(EV71). On the contrary, anti-apoptotic pathway, such as PI3K/Akt pathway, is …
Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of enterovirus 71
Viruses have been known to subvert the anti-apoptotic pathways of the host cell in order to
delay apoptosis. However, the mechanisms utilized by enterovirus 71 (EV71) to mediate anti …
delay apoptosis. However, the mechanisms utilized by enterovirus 71 (EV71) to mediate anti …
Enterovirus 71 2B induces cell apoptosis by directly inducing the conformational activation of the proapoptotic protein Bax
H Cong, N Du, Y Yang, L Song, W Zhang… - Journal of virology, 2016 - Am Soc Microbiol
To survive and replicate within a host, many viruses have evolved strategies that target
crucial components within the apoptotic cascade, leading to either inhibition or induction of …
crucial components within the apoptotic cascade, leading to either inhibition or induction of …
Characteristics of enterovirus 71-induced cell death and genome scanning to identify viral genes involved in virus-induced cell apoptosis
J Bai, X Chen, Q Liu, X Zhou, JE Long - Virus research, 2019 - Elsevier
Abstract Enterovirus 71 (EV71) causes hand-foot-and-mouth disease and severe neural
complications in infants and young children. Viral pathogenesis is associated with virus …
complications in infants and young children. Viral pathogenesis is associated with virus …
The interplays between autophagy and apoptosis induced by enterovirus 71
X Xi, X Zhang, B Wang, T Wang, J Wang, H Huang… - PloS one, 2013 - journals.plos.org
Background Enterovirus 71 (EV71) is the causative agent of human diseases with distinct
severity, from mild hand, foot and mouth disease to severe neurological syndromes, such as …
severity, from mild hand, foot and mouth disease to severe neurological syndromes, such as …
Differential apoptosis gene expressions of rhabdomyosarcoma cells in response to enterovirus 71 infection
W Shi, X Li, X Hou, H Peng, Q Jiang, M Shi, Y Ji… - BMC infectious …, 2012 - Springer
Abstract Background Enterovirus 71 (EV71) infection can induce the apoptosis of infected
cells. The aim of this study is to explore the effect of EV71 infection on apoptosis …
cells. The aim of this study is to explore the effect of EV71 infection on apoptosis …
Regulation of host responses and viral replication by the mitogen-activated protein kinases in intestinal epithelial cells infected with Enterovirus 71
C Wang, L Gao, Y Jin, CJ Cardona, Z Xing - Virus research, 2015 - Elsevier
Abstract Enterovirus 71 (EV71) has become an important neurotropic enterovirus in children
since the eradication of the poliovirus. A cytokine storm with elevated levels of …
since the eradication of the poliovirus. A cytokine storm with elevated levels of …
Enterovirus 71 3C promotes apoptosis through cleavage of PinX1, a telomere binding protein
J Li, Y Yao, Y Chen, X Xu, Y Lin, Z Yang… - Journal of …, 2017 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71) is an emerging pathogen causing hand, foot, and mouth
disease (HFMD) and fatal neurological diseases in infants and young children due to their …
disease (HFMD) and fatal neurological diseases in infants and young children due to their …
Calcium flux and calpain-mediated activation of the apoptosis-inducing factor contribute to enterovirus 71-induced apoptosis
JR Lu, WW Lu, JZ Lai, FL Tsai… - Journal of General …, 2013 - microbiologyresearch.org
Enterovirus 71 (EV71) is a causative agent of an array of childhood diseases with severe
neurological manifestations implicated. EV71 infection is known to induce caspase …
neurological manifestations implicated. EV71 infection is known to induce caspase …
Enterovirus 71 induces apoptosis of SH‑SY5Y human neuroblastoma cells through stimulation of endogenous microRNA let-7b expression
X Du, H Wang, F Xu, Y Huang… - Molecular medicine …, 2015 - spandidos-publications.com
Abstract Enterovirus 71 (EV71) is a pathogenic microorganism that causes hand, foot and
mouth disease. However, the epigenetic mechanisms behind how EV71 regulates host cell …
mouth disease. However, the epigenetic mechanisms behind how EV71 regulates host cell …