High-density sub-100-nm peptide-gold nanoparticle complexes improve vaccine presentation by dendritic cells in vitro

AY Lin, J Lunsford, AS Bear, JK Young… - Nanoscale Research …, 2013 - Springer
Nanocarriers have been explored to improve the delivery of tumor antigens to dendritic cells
(DCs). Gold nanoparticles are attractive nanocarriers because they are inert, non-toxic, and …

Homogeneous conjugation of peptides onto gold nanoparticles enhances macrophage response

NG Bastús, E Sánchez-Tilló, S Pujals, C Farrera… - ACS …, 2009 - ACS Publications
Murine bone marrow macrophages were able to recognize gold nanoparticle peptide
conjugates, while peptides or nanoparticles alone were not recognized. Consequently, in …

Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

YSS Yang, KD Moynihan, A Bekdemir… - Biomaterials …, 2019 - pubs.rsc.org
We sought to develop a nanoparticle vehicle that could efficiently deliver small molecule
drugs to target lymphocyte populations. The synthesized amphiphilic organic ligand …

In vivo gold nanoparticle delivery of peptide vaccine induces anti‐tumor immune response in prophylactic and therapeutic tumor models

JPM Almeida, AY Lin, ER Figueroa, AE Foster… - Small, 2015 - Wiley Online Library
Gold nanoparticles (AuNPs) are promising vehicles for cancer immunotherapy, with
demonstrated efficacy in immune delivery and innate cell stimulation. Nevertheless, their …

Gold nanoparticles stabilize peptide-drug-conjugates for sustained targeted drug delivery to cancer cells

K Kalimuthu, BC Lubin, A Bazylevich… - Journal of …, 2018 - Springer
Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective
strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges …

[HTML][HTML] Injectable host-guest gel nanovaccine for cancer immunotherapy against melanoma

K Xu, Y Wen, X Zhang, Y Liu, D Qiu, B Li… - Materials Today …, 2022 - Elsevier
Despite the extensive development of peptide-based tumor antigen vaccines, the field still
faces up enormous challenges from lacking clinical efficacy. Here, we report the design and …

Gold nanocluster-based vaccines for dual-delivery of antigens and immunostimulatory oligonucleotides

Y Tao, Y Zhang, E Ju, H Ren, J Ren - Nanoscale, 2015 - pubs.rsc.org
We here report a facile one-pot synthesis of fluorescent gold nanoclusters (AuNCs) via the
peptide biomineralization method, which can elicit specific immunological responses. The …

A facile approach for synthesis and intracellular delivery of size tunable cationic peptide functionalized gold nanohybrids in cancer cells

K Bansal, M Aqdas, M Kumar, R Bala… - Bioconjugate …, 2018 - ACS Publications
Peptide-based drug delivery systems have become a mainstay in the contemporary
medicinal field, resulting in the design and development of better pharmaceutical …

Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for cancer immunotherapy.

S Ahn, IH Lee, S Kang, D Kim, M Choi… - Advanced healthcare …, 2014 - europepmc.org
Gold nanoparticles displaying tumor-associated self-antigens as a potential vaccine for
cancer immunotherapy. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

Non-covalent glycosylated gold nanoparticles/peptides nanovaccine as potential cancer vaccines

L Zeng, Z Liao, W Li, Q Yuan, P Wu, Z Gu, Z Liu… - Chinese Chemical …, 2020 - Elsevier
Herein, we firstly developed a non-covalent glycosylated gold nanoparticles/peptides
nanovaccine which is assembled by β-cyclodextrin (β-CD) based host-guest recognitions …