[PDF][PDF] Second versus first-generation drug-eluting stents

K Chitkara, A Gershlick - J. Interv. Cardiol, 2010 - assets.radcliffecardiology.com
Drug-eluting stents (DES) have demonstrated their superiority over bare-metal stents (BMS)
with respect to in-stent restenosis and the need for repeat revascularisation. BMS and first …

Drug eluting stents: maximising benefit and minimising cost

J Gunn, AC Morton, C Wales, CMH Newman… - Heart, 2003 - heart.bmj.com
Drug eluting stents: maximising benefit and minimising cost | Heart Skip to main content
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Vascular Lesion–Specific Drug Delivery Systems: JACC State-of-the-Art Review

D Marlevi, ER Edelman - Journal of the American College of Cardiology, 2021 - jacc.org
Drug delivery is central to modern cardiovascular care, where drug-eluting stents,
bioresorbable scaffolds, and drug-coated balloons all aim to restore perfusion while …

Antiproliferative coatings for the treatment of coronary heart disease: what are the targets and which are the tools?

EJ Smith, MT Rothman - Journal of Interventional Cardiology, 2003 - Wiley Online Library
Since the advent of percutaneous coronary intervention (PCI) for stenosing coronary
disease, restenosis has remained a clinical problem. Despite the emergence and evolution …

[HTML][HTML] Navigating the regulatory pathway for medical devices—a conversation with the FDA, clinicians, researchers, and industry experts

AE Lottes, KJ Cavanaugh, YYF Chan, VJ Devlin… - Journal of …, 2022 - Springer
Successful translation of new and innovative medical products from concept to clinical use is
a complex endeavor that requires understanding and overcoming a variety of challenges. In …

Paclitaxel-eluting stents: current clinical experience

E Grube, L Buellesfeld - American Journal of Cardiovascular Drugs, 2004 - Springer
In the past few years, drug-eluting stents have emerged as one of the most promising
technologies in the field of interventional cardiology. Loaded with antiproliferative and anti …

A review of current devices and a look at new technology: drug-eluting stents

G Nakazawa, AV Finn, FD Kolodgie… - Expert review of medical …, 2009 - Taylor & Francis
Drug-eluting stents (DES) have become the standard of care for the treatment of coronary
artery disease. However, late stent thrombosis has emerged as a major concern, especially …

Multidimensional pharmacokinetic models applied to the design of drug-eluting stents

P Zunino - Cardiovascular Engineering: An International Journal, 2004 - Springer
Drug-eluting stents are cardiovascular stents able to release a medical drug after
implantation. The medical drug is, in general, aimed at healing the vascular tissues injured …

Update on bioabsorbable stents: from bench to clinical

RON Waksman - Journal of Interventional Cardiology, 2006 - Wiley Online Library
Permanent metallic stents are associated with limitations such as continued mechanical
stress, transfer to the tissue, and continued biological interaction with the surrounding tissue …

Defining drug and target protein distributions after stent-based drug release: Durable versus deployable coatings

AR Tzafriri, F Garcia-Polite, X Li, J Keating… - Journal of controlled …, 2018 - Elsevier
Background Innovations in drug eluting stent designs make it increasingly important to
develop models for differentiating performance through spatial definition of drug, receptor …