TISSUE nitric oxide (NO) concentration was investigated in relation to ion-homeostasis
disturbance in the cat model of focal cerebral ischaemia. An NO electrode, a Ca 2+ …

Using a porphyritic microsensor, we measured the cortical NO concentration within ischemic
tissue during 2 h of middle cerebral artery (MCA) occlusion and 1 h of reperfusion in the rat …

The results of our continuing studies on the role of nitric oxide (NO) in cellular mechanisms
of ischemic brain damage as well as related reports from other laboratories are summarized …

Nitric oxide (NO) is considered to be associated with the pathogenesis of cerebral ischemic
injury. In the present study, NO production was continuously monitored employing in vivo …

Cortical depolarization was investigated in a topographic gradient of ischemic density after 1-
hour transient middle cerebral artery occlusion in halothane-anesthetized cats. A laser …

Nitric oxide (NO) is a potent vasodilator produced by nitric oxide synthase (NOS). We tested
the following hypotheses:(1) cerebral blood flow (CBF) is NO dependent,(2) NO contributes …

Background and Purpose—Excessive release of nitric oxide (NO) has been implicated in the
pathophysiology of neurodegeneration in ischemic stroke. We compared intracerebral …

Nitrogen monoxide (NO) has recently emerged as an important mediator of cellular and
molecular events which impacts the pathophysiology of cerebral ischemia. Although …

Abstract Changes in the nitric oxide (NO) system of the rat cerebral cortex were investigated
by immunohistochemistry, immunoblotting, NO synthase (NOS) activity assay, and magnetic …

Nitric oxide, a potent vasodilator and an inhibitor of platelet aggregation, may be beneficial
in the early stages of focal cerebral ischemia as it may facilitate collateral blood flow to the …