The epitope sequences within the hemagglutinin (HA) of influenza A virus H3N2 at amino
acid residues 173–181 and 227–239 that forms anti-parallel β-sheet structure are similarly …

Most neutralizing antibodies elicited during influenza virus infection or by vaccination have a
narrow spectrum because they usually target variable epitopes in the globular head region …

Neutralizing antibodies that target the hemagglutinin of influenza virus either inhibit binding
of hemagglutinin to cellular receptors or prevent the low-pH-induced conformational change …

ABSTRACT A human monoclonal heterosubtypic antibody, MAb 3.1, with its heavy chain
encoded by VH3-30, was isolated using phage display with immobilized hemagglutinin (HA) …

The hemagglutinin protein of H3N2 influenza viruses is the major target of neutralizing
antibodies induced by infection and vaccination. However, the virus frequently escapes …

Influenza A virus infection is a persistent threat to public health worldwide due to its ability to
evade immune surveillance through rapid genetic drift and shift. Current vaccines against …

Seasonal influenza viruses are highly contagious, leading to 290,000–650,000 mortalities
every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted …

Starting with nine plaques of influenza A/Kamata/14/91 (H3N2) virus, we selected mutants in
the presence of monoclonal antibody 203 (mAb203). In total, amino acid substitutions were …

A monoclonal antibody LMBH5 was derived from mice which had been immunized with
A/Victoria/3/75 (H3Ng)-type recombinant, secreted hemagglutinin (HA), and were …

Influenza A (H3N2) viruses are associated with outbreaks worldwide and can cause disease
with severe complications. The impact can be reduced by vaccination, which induces …