Equine neutrophils and their role in ischemia reperfusion injury and lung inflammation

SL Anderson, B Singh - Cell and Tissue Research, 2018 - Springer
Horses are susceptible to a multitude of inflammatory conditions that are characterized by a
strong neutrophilic response. Here, we review basic equine neutrophil biology and explore …

Direct stimulation of the oxidative activity of isolated equine neutrophils by TNF-alpha and IL-1beta

H Benbarek, G Deby-Dupont, C Deby… - Veterinary immunology …, 2008 - Elsevier
The capacity of the two cytokines TNF-alpha and IL-1beta to directly stimulate the oxidative
activity of polymorphonuclear neutrophils remains debated. The purpose of this study was to …

Functional characterization of equine neutrophils in response to calcium ionophore A23187 and phorbol myristate acetate ex vivo

T Moore, J Wilcke, C Chilcoat, P Eyre… - Veterinary immunology …, 1997 - Elsevier
Equine neutrophils (PMN) play a critical role in inflammatory processes in horses. The
objective of this study was to characterize equine PMN function ex vivo following stimulation …

Evaluation of lipopolysaccharide-induced activation of equine neutrophils

DJ Weiss, OA Evanson - American journal of veterinary research, 2002 - Am Vet Med Assoc
Objective—To evaluate lipopolysaccharide (LPS)-induced activation of equine neutrophils
in blood. Sample Population—Blood samples from 5 healthy adult Thoroughbreds …

IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo

A Lavoie-Lamoureux, K Moran… - … of Physiology-Lung …, 2010 - journals.physiology.org
Neutrophils are potent contributors to the lung pathophysiological changes occurring in
allergic airway inflammation, which typically involve T helper type 2 (Th2) cytokine …

Pulmonary neutrophil recruitment, activation and clearance in equine chronic obstructive pulmonary disease

TJ Brazil - Annexe Thesis Digitisation Project 2018 Block 18, 2000 - era.ed.ac.uk
Acute COPD was induced in susceptible horses by exposure to a 5 h hay/straw challenge.
The kinetics and function of airspace neutrophils harvested by bronchoalveolar lavage and …

Characterization of extracellular trap production and release by equine neutrophils in response to different stimuli

J Quiroga, B Cortes, J Sarmiento, G Morán… - Developmental & …, 2024 - Elsevier
Abstract This study explores Neutrophil Extracellular Trap (NET) formation in equine
neutrophils, which is crucial for eliminating infections and is implicated in various equine …

An in vitro whole blood model to test the effects of different stimuli conditions on the release of myeloperoxidase and elastase by equine neutrophils

JD Ceusters, DA Serteyn, G Minguet… - Veterinary immunology …, 2012 - Elsevier
Horses are particularly sensitive and exposed to excessive inflammatory responses evolving
toward an important stimulation of polymorphonuclear neutrophils (PMNs). The aim of this …

A comparison of foal and adult horse neutrophil function using flow cytometric techniques

C McTaggart, JV Yovich, J Penhale… - Research in Veterinary …, 2001 - Elsevier
Flow cytometric assays were used to compare phagocytic and oxidative burst activity of
neutrophils from healthy foals less than 7 days of age with the activity of cells from healthy …

Role of neutrophils in equine asthma

B Uberti, G Morán - Animal health research reviews, 2018 - cambridge.org
Neutrophilic bronchiolitis is the primary lesion in asthma-affected horses. Neutrophils are
key actors in host defense, migrating toward sites of inflammation and infection, where they …