Benchmarking pathway interaction network for colorectal cancer to identify dysregulated pathways

Q Wang, CJ Shi, SH Lv - Brazilian Journal of Medical and Biological …, 2017 - SciELO Brasil
Different pathways act synergistically to participate in many biological processes. Thus, the
purpose of our study was to extract dysregulated pathways to investigate the pathogenesis …

A gene expression signature associated with overall survival in patients with hepatocellular carcinoma suggests a new treatment strategy

JP Gillet, JB Andersen, JP Madigan, S Varma… - Molecular …, 2016 - ASPET
Despite improvements in the management of liver cancer, the survival rate for patients with
hepatocellular carcinoma (HCC) remains dismal. The survival benefit of systemic …

Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6* 10 polymorphism and identification of ANGPTL6 as a new diagnostic and …

G Hu, F Gao, G Wang, Y Fang, Y Guo, J Zhou… - Journal of Translational …, 2021 - Springer
Background Although an association between the cytochrome P4502D6 (CYP2D6)* 10
(100C> T) polymorphism and hepatocellular carcinoma (HCC) is known, the mechanism …

[PDF][PDF] Critical genes of hepatocellular carcinoma revealed by network and module analysis of RNA-seq data

MR Yang, Y Zhang, XX Wu… - Eur Rev Med Pharmacol …, 2016 - europeanreview.org
OBJECTIVE: RNA-seq data of he-patocellular carcinoma (HCC) was analyzed to identify
critical genes related to the pathogenesis and prognosis. MATERIALS AND METHODS …

Identification of key candidate genes and pathways in hepatocellular carcinoma by integrated bioinformatical analysis

T Xing, T Yan, Q Zhou - Experimental and therapeutic …, 2018 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is one of the most common malignant neoplasms
worldwide, however the underlying mechanisms and gene signatures of HCC are unknown …

Integrated omics landscape of hepatocellular carcinoma suggests proteomic subtypes for precision therapy

X Xing, E Hu, J Ouyang, X Zhong, F Wang, K Liu… - Cell Reports …, 2023 - cell.com
Patients with hepatocellular carcinoma (HCC) at the same clinical stage can have extremely
different prognoses, and molecular subtyping provides an opportunity for individualized …

Identification of key genes and pathways in hepatocellular carcinoma: A preliminary bioinformatics analysis

M Wu, Z Liu, A Zhang, N Li - Medicine, 2019 - journals.lww.com
Background: Hepatocellular carcinoma (HCC) is one of the most prevalent cancers
worldwide. However, the precise mechanisms of the development and progression of HCC …

[HTML][HTML] Identifying drug candidates for hepatocellular carcinoma based on differentially expressed genes

J Xing, Q Shi, J Zhao, Z Yu - American Journal of Translational …, 2020 - ncbi.nlm.nih.gov
The prognosis for patients with advanced hepatocellular carcinoma (HCC) is extremely
poor, mainly due to rapid progression and a paucity of effective drugs. Genome-wide …

Temporal identification of dysregulated genes and pathways in clear cell renal cell carcinoma based on systematic tracking of disrupted modules

SM Wang, ZQ Sun, HY Li, J Wang… - … methods in medicine, 2015 - Wiley Online Library
Objective. The objective of this work is to identify dysregulated genes and pathways of
ccRCC temporally according to systematic tracking of the dysregulated modules of …

Identification of key genes associated with the progression of intrahepatic cholangiocarcinoma using weighted gene co‑expression network analysis

Z Ye, Z Zeng, D Wang, S Lei, Y Shen… - Oncology …, 2020 - spandidos-publications.com
The present study aimed to identify the key genes that are associated with the progression of
intrahepatic cholangiocarcinoma through weighted gene co‑expression network analysis …