Affective disorders, including major depression and bipolar disorder, are thought to stem
from alterations in neurotransmitter transduction pathways, but recent evidence implicates …

Mitochondria are cellular organelles involved in several biological processes, especially in
energy production. Several studies have found a relationship between mitochondrial …

Depression is a common mental illness with mood disorders as the main clinical feature. In
recent years numerous studies have shown that mitochondrial function and structure are …

Major depressive disorder (MDD) is an independent risk factor for the development of type 2
diabetes (T2DM) and cardiovascular disorders (CVD). Vice versa, patients suffering from …

Major depression is the most common mental disorder and a leading cause of years lived
with disability. In addition to the burden attributed to depressive symptoms and reduced daily …

Depression is a leading cause of disability in the United States. Up until this point in time, the
most widely accepted theory as to the etiology of depression is the monoamine theory; a …

Background: Depression is the most debilitating neuropsychiatric disorder with significant
impact on socio-occupational and well being of individual. The exact pathophysiology of …

Depression is a serious mental disorder manifested by depressed mood, pessimistic
thoughts, feelings of worthlessness, feelings of guilt, tearfulness, reduced or increased …

Major depressive disorder (MDD) is widely accepted as having a heterogenous
pathophysiology involving a complex mixture of systemic and CNS processes. A …

There is controversy about depression being a physical illness, in part because a
reproducible, sensitive, and specific biologic marker is not available. However, there is …