Dissolution of poorly soluble drugs can be improved by wet-milling their suspensions and
drying the suspensions to form nanocomposites. Different classes of dispersants and their …

We explore the impact of various polymers and their molecular weight on the stabilization of
wet-milled suspensions of itraconazole (ITZ), a poorly soluble drug, and its dissolution from …

Bioavailability of a poorly soluble drug can be improved by preparing a drug
nanosuspension and subsequently drying it into nanocomposite microparticles (NCMPs) …

Without a proper stabilizer formulation, drug nanoparticles can aggregate during the
formation of nanosuspensions and their drying into composite powders, which in turn can …

Formation of core-shell nanocomposites of Fenofibrate and Itraconazole, model poorly water
soluble drugs, via fluidized bed (FB) coating of their well-stabilized high drug loaded …

Enhanced recovery/dissolution of two wet media-milled, poorly water-soluble drugs,
Griseofulvin (GF) and Azodicarbonamide (AZD), incorporated into nanocomposite …

This study focuses on the preparation of sub-100 μm freely flowing yet fast dissolving core–
shell nanocomposite powders via fluidized bed (FB) coating of poorly water-soluble drug …

Purpose Drying of nanosuspensions can cause destabilization of the particles, leading to
irreversible aggregation. In order to prepare an effective solid dosage form for a …

Nanoextrusion was used to produce extrudates of griseofulvin, a poorly water-soluble drug,
with the objective of examining the impact of drug particle size and polymeric matrix type …

Drug nanoparticles embedded in a dispersant matrix as a secondary phase, ie, drug-laden
nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and …