Two-drug treatment approaches in HIV: finally getting somewhere?
SG Kelly, AN Nyaku, BO Taiwo - Drugs, 2016 - Springer
The advent of combination antiretroviral therapy (ART) has significantly decreased AIDS-
related morbidity and mortality. Nevertheless, the benefits of ART are only realized through …
related morbidity and mortality. Nevertheless, the benefits of ART are only realized through …
Ready for HIV Dual Therapy?-New Data from International HIV/AIDS Society 2017.
GA Yendewa, RA Salata - AIDS reviews, 2017 - europepmc.org
The introduction of combination antiretroviral therapy (ART) in the 1990s has fundamentally
transformed the landscape of HIV medicine, greatly improved disease morbidity and …
transformed the landscape of HIV medicine, greatly improved disease morbidity and …
Is antiretroviral two-drug regimen the new standard for HIV treatment in naive patients?
E Dupont, JC Yombi - AIDS reviews, 2019 - search.ebscohost.com
The use of a combination antiretroviral therapy (cART) has changed dramatically the
prognosis and the life expectancy of people living with HIV. The current treatment guidelines …
prognosis and the life expectancy of people living with HIV. The current treatment guidelines …
Dual therapy treatment strategies for the management of patients infected with HIV: a systematic review of current evidence in ARV-naive or ARV-experienced …
JG Baril, JB Angel, MJ Gill, J Gathe, P Cahn… - PLoS …, 2016 - journals.plos.org
Objective We reviewed the current literature regarding antiretroviral (ARV)-sparing therapy
strategies to determine whether these novel regimens can be considered appropriate …
strategies to determine whether these novel regimens can be considered appropriate …
Dual antiretroviral therapy for HIV infection
V Soriano, JV Fernandez-Montero… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: For two decades, triple combinations of antiretrovirals have been the standard
treatment for HIV infection. The challenges of such lifelong therapy include long-term side …
treatment for HIV infection. The challenges of such lifelong therapy include long-term side …
Two‐drug vs. three‐drug combinations for HIV‐1: Do we have enough data to make the switch?
Three‐drug combination antiretroviral therapy (ART) became available in 1996, dramatically
improving the prognosis of people living with HIV. The clinical benefits of ART are due to the …
improving the prognosis of people living with HIV. The clinical benefits of ART are due to the …
Efficacy and safety of contemporary dual-drug antiretroviral regimens as first-line treatment or as a simplification strategy: a systematic review and meta-analysis
Background Some guidelines recommended two-drug antiretroviral therapies as alternative
regimens to triple therapy in selected patients with the aim of reducing drug burden and …
regimens to triple therapy in selected patients with the aim of reducing drug burden and …
State of the art of dual therapy in 2015
S Nozza, V Svicher, A Saracino, G d'Ettorre… - AIDS reviews, 2015 - iris.uniroma1.it
Dual therapy refers to combinations of two antiretroviral drugs applied in different clinical
settings; they are considered and studied due to possibly reduced drug toxicities. In …
settings; they are considered and studied due to possibly reduced drug toxicities. In …
Real-world experience with two-drug regimens in HIV-1-infected patients beyond the indication of clinical trials: 48 weeks' results
A Arancón Pardo, M Moreno Palomino… - AIDS research and …, 2021 - liebertpub.com
Data on two-drug regimens (2DRs) have shown high efficacy and tolerability in treatment-
naive and treatment-experienced HIV-1 patients. Current guidelines recommend 2DRs as …
naive and treatment-experienced HIV-1 patients. Current guidelines recommend 2DRs as …
Two'sa company, three'sa crowd: A review of initiating or switching to a two-drug antiretroviral regimen in treatment-naïve and treatment-experienced patients living …
M Badowski, SE Pérez, D Silva, A Lee - Infectious Diseases and Therapy, 2020 - Springer
Introduction As HIV has become a manageable chronic condition, a renewed and increased
interest in challenging traditional three-drug HIV therapies and moving toward two-drug …
interest in challenging traditional three-drug HIV therapies and moving toward two-drug …