Background: Hepatic derangements and liver injury following the Fontan operation (FO) may
progress in some cases to hepatic fibrosis (HF) and cirrhosis. The respective roles of …

Purpose Liver biopsy (LB) is still considered the “gold standard” for hepatological
evaluation, but recently noninvasive methods have attempted to replace this invasive …

AIM To investigate the performance of transient elastography (TE) for diagnosis of fibrosis in
patients with autoimmune hepatitis-primary biliary cholangitis (AIH-PBC) overlap syndrome …

Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …

Objectives: Biliary atresia (BA), a congenital idiopathic obliterative cholangiopathy, rapidly
leads to liver cirrhosis and liver failure if untreated. A timely Kasai portoenterostomy (KP) …

Aim Patients who undergo the Fontan procedure for complex congenital heart disease are
prone to liver cirrhosis. Liver stiffness (LS) reflects liver fibrosis stage in patients with chronic …

Objective To investigate the expression and function of transforming growth factor (TGF)-β1
and Smad2 in liver fibrosis of biliary atresia (BA). Methods Liver biopsy specimens were …

Abstract Introduction Liver stiffness measurements (LSMs) using transient elastography (TE)
provide a noninvasive means to assess liver fibrosis that correlate with hepatic cholestasis …

Introduction Our previous work demonstrated that the transforming-growth factor (TGF) β
pathway plays a central role in the liver fibrosis associated with experimental biliary atresia …