Asthma is an extremely prevalent chronic inflammatory disease of the airway where innate
and adaptive immune systems participate collectively with epithelial and other structural …

Our understanding on the immunological roles of pathogen recognition in innate immunity
has vastly increased over the past 20 years. Nucleotide-binding oligomerization domain …

The lung is a particularly vulnerable organ at the interface of the body and the exterior
environment. It is constantly exposed to microbes and particles by inhalation. The innate …

Key intracytosolic pattern recognition receptors of innate immunity against bacterial
infections are nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs). We …

To cite this article: Bogefors J, Rydberg C, Uddman R, Fransson M, Månsson A, Benson M,
Adner M, Cardell LO. Nod1, Nod2 and Nalp3 receptors, new potential targets in treatment of …

Nucleotide-binding oligomerization domain 2 (NOD2) recognizes pathogens associated
with the development of asthma. Moreover, NOD2 adjuvants are used in vaccine design to …

The cytosolic nucleotide oligomerization domain (NOD)-like receptors NOD1 and NOD2 are
important contributors to the intracellular recognition of pathogens including Chlamydophila …

Pneumonia is caused by both viral and bacterial pathogens and is responsible for a
significant health burden in the Unites States. The innate immune system is the human …

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are a family of
intracellular sensors that have key roles in innate immunity and inflammation. Whereas …

NOD-like receptors (NLRs) comprise a family of cytosolic proteins that have been implicated
as ancient cellular sentinels mediating protective immune responses elicited by intracellular …