Memory consolidation in the neocortex is thought to be mediated in part by bi-directional
modifications of synaptic strength. The sensorimotor cortex shows marked spontaneous …

Activity-dependent reductions in synaptic efficacy are central components of recent models
of cortical learning and memory. Here, we have examined long-term synaptic depression …

Freely moving rats received high-frequency stimulation of the perforant path-granule cell
pathway during slow-wave sleep (SWS) and during a still-alert (SAL) behavioral state …

Long-term depression (LTD) is one of the most widely investigated models of the synaptic
mechanisms underlying learning and memory. Previous research has shown that induction …

In a rest period immediately after a task, neurons in the hippocampus, neocortex, and
striatum exhibit spatiotemporal correlation patterns resembling those observed during the …

We have examined the efficacy of a recently introduced protocol for inducing homosynaptic
long-term depression (LTD) in area CA1 of the anesthetized rat (Thiels et al.[1994] J …

Intrinsic persistent spiking mechanisms in medial entorhinal cortex (mEC) neurons may play
a role in active maintenance of working memory. However, electrophysiological studies of …

Homosynaptic long-term depression (LTD) is reported to occur in field CA1 of hippocampal
slices collected from immature brains. Because the effect has been postulated to be a …

Thalamic stimulation at frequencies between 5 and 15 Hz elicits incremental or
'augmenting'cortical responses. Augmenting responses can also be evoked in cortical slices …

It is well established that neuronal transmission from the entorhinal cortex through the
dentate gyrus via the perforant path is dependent on behavioral state. To further study the …