Simultaneous quantification of 38 psychotropic drugs and relevant metabolites in blood using LC–MS-MS

R Zhu, X Dong, D Zhang, X Liu, Y Ye… - Journal of Analytical …, 2021 - academic.oup.com
The trend for the concomitant prescription of antidepressants and antipsychotics is
increasing. This calls for a veracious screening and quantifying method for forensic and …

[HTML][HTML] Development and validation of a fast UPLC-MS/MS screening method for the detection of 68 psychoactive drugs and metabolites in whole blood and …

R Barone, A Giorgetti, R Cardella, F Rossi… - … of Pharmaceutical and …, 2023 - Elsevier
We report a rapid and sensitive LC-MS/MS method that allows the simultaneous detection of
68 commonly prescribed antidepressants, benzodiazepines, neuroleptics, and metabolites …

Quantitative method validation for the analysis of 27 antidepressants and metabolites in plasma with ultraperformance liquid chromatography–tandem mass …

MMR Fernández, SMR Wille… - Therapeutic Drug …, 2012 - journals.lww.com
A fast and selective ultraperformance liquid chromatographic–tandem mass spectrometric
method was developed and validated for the simultaneous quantification of amitriptyline …

Simultaneous and sensitive analysis of fourth-generation antidepressants in human plasma by ultra-performance liquid chromatography–tandem mass spectrometry

K Iwakura, T Ogawa, H Hattori, M Iwai, O Suzuki… - Forensic …, 2014 - Springer
A sensitive method for simultaneous analysis of nine fourth-generation antidepressants in
human plasma by ultra-performance liquid chromatography–tandem mass spectrometry …

Antidepressants detection and quantification in whole blood samples by GC–MS/MS, for forensic purposes

L Truta, AL Castro, S Tarelho, P Costa… - … of pharmaceutical and …, 2016 - Elsevier
Depression is among the most prevalent psychiatric disorders of our society, leading to an
increase in antidepressant drug consumption that needs to be accurately determined in …

Determination of 13 antidepressants in blood by UPLC-MS/MS with supported liquid extraction pretreatment

W Ma, X Gao, H Guo, W Chen - Journal of Chromatography B, 2021 - Elsevier
Antidepressants are widely used nowadays. Due to the potential detrimental consequences
and involvement in forensic cases, therapeutic drug monitoring of antidepressants is …

Development and validation of a method for quantification of 28 psychotropic drugs in postmortem blood samples by modified Micro-QuEChERS and LC–MS-MS

TB Rodrigues, DR Morais… - Journal of Analytical …, 2021 - academic.oup.com
The development of new sample preparation alternatives in analytical toxicology leading to
quick, effective, automated and environmentally friendly procedures is growing in …

Validation of a simple, fast liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 40 antidepressant drugs or their …

M Degreef, ALN van Nuijs, KE Maudens - Clinica Chimica Acta, 2018 - Elsevier
Introduction Antidepressant (AD) use has increased significantly over the last decades.
Therapeutic drug monitoring is recommended for compliance, toxicity and treatment …

Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC–MS/MS

M Di Rago, E Saar, LN Rodda, S Turfus… - Forensic Science …, 2014 - Elsevier
The aim of this study was to develop an LC–MS/MS based screening technique that covers
a broad range of acidic and neutral drugs and poisons by combining a small sample volume …

Qualitative and semi-quantitative screening of selected psychoactive drugs in blood: Usefulness of liquid chromatography–triple quadrupole and quadrupole time-of …

M Degreef, EM Berry, A Covaci, KEK Maudens… - … of Chromatography B, 2022 - Elsevier
Routine toxicological analysis requires broad screening for a large number of
therapeutically prescribed and other compounds, and/or their metabolites. This article …