Skeletal muscle shows high plasticity in response to external demand. Moreover, adult
skeletal muscle is capable of complete regeneration after injury, due to the properties of …

Skeletal muscle fibers are malleable and undergo rapid remodeling in response to
increased contractile activity (ie, exercise) or prolonged periods of muscle inactivity (eg …

Because of their contractile activity and their high oxygen consumption and metabolic rate,
skeletal muscles continually produce moderate levels of reactive oxygen and nitrogen …

Muscle contraction results in generation of reactive oxygen and nitrogen species (RONS) at
a rate determined by the intensity, frequency, and duration of the exercise protocols …

Recent research highlights the importance of redox signalling pathway activation by
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …

It is well established that contracting skeletal muscles produce free radicals. Given that
radicals are known to play a prominent role in the pathogenesis of several diseases, the …

Skeletal muscle contraction is associated with the production of ROS due to altered O2
distribution and flux in the cell. Despite a highly efficient antioxidant defense, a small surplus …

Exercise imposes cellular stress on contracting skeletal muscle fibers, forcing them to
complete molecular adaptations to maintain homeostasis. There is mounting evidence that …

Increased reactive oxygen species (ROS) production is crucial to the remodelling that occurs
in skeletal muscle in response to both exercise training and prolonged periods of disuse …

It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …