Expression and characterization of the JAK kinase and STAT protein from brine shrimp, Artemia franciscana

CH Cheng, GD Chen, MS Yeh, CY Chu, YL Hsu… - Fish & Shellfish …, 2010 - Elsevier
In this study, we isolated and characterized both JAK and STAT genes from Artemia, Artemia
franciscana. Although AfJAK showed only 19% identity (33% similarity) to the Drosophila …

Cloning and expression analysis of Janus activated kinase family genes from spotted seabass (Lateolabrax maculatus)

K Fan, Q Gao, C Cai, Y Xie, Z Qi, Z Sun, J Xie… - Developmental & …, 2024 - Elsevier
Janus kinases (JAKs) are important components of the JAK-STAT signaling pathway and
play vital roles in innate immunity, autoimmune diseases, and inflammation. However …

The JAK and STAT family members of the mandarin fish Siniperca chuatsi: molecular cloning, tissues distribution and immunobiological activity

CJ Guo, YF Zhang, LS Yang, XB Yang, YY Wu… - Fish & Shellfish …, 2009 - Elsevier
The JAK/STAT signal transduction pathway plays a critical role in host defence against viral
and bacterial infections. In the present study, we report cDNA cloning and characterization of …

Three members in JAK/STAT signal pathway from the sea cucumber Apostichopus japonicus: Molecular cloning, characterization and function analysis

Y Shao, C Li, W Zhang, X Duan, Y Li, Q Han… - Fish & shellfish …, 2015 - Elsevier
The JAK/STAT signal transduction pathway plays a critical role in host defense against
bacterial infections. In the present study, we firstly cloned the full-length cDNAs of three …

The SOCS and STAT from JAK/STAT signaling pathway of kuruma shrimp Marsupenaeus japonicus: molecular cloning, characterization and expression analysis

S Okugawa, T Mekata, M Inada, K Kihara… - Molecular and Cellular …, 2013 - Elsevier
Signal transducer and activators of transcription (STAT) gene, suppressors of cytokine
signaling (SOCS) has been isolated from kuruma shrimp, Marsupenaeus japonicus and …

Janus kinase 1 in Megalobrama amblycephala: Identification, phylogenetic analysis and expression profiling after Aeromonas hydrophila infection

Q Sun, J Zhang, J Wang, H Wang, Z Gao… - Fish & Shellfish …, 2023 - Elsevier
Abstract Janus kinase 1 (JAK1), a member of the JAK family, plays an essential and non-
redundant role in the mammalian immune system. However, the potential role of JAK1 in fish …

[HTML][HTML] Molecular Characterization and Expression Analysis of Four Janus Kinases (JAK1, JAK2a, JAK3 and TYK2) from Golden Pompano (Trachinotus ovatus)

Y Xie, M Chen, P Han, X Liang, M Yang, Z Lu, Y Wei - Fishes, 2023 - mdpi.com
Golden pompano, Trachinotus ovatus, is a perciform fish with great economic value and is
widely cultured in the coastal areas of China. The wide occurrence of bacterial, parasitic and …

[HTML][HTML] Molecular cloning and expression analysis of the STAT1 gene from olive flounder, Paralichthys olivaceus

EM Park, JH Kang, JS Seo, GD Kim, J Chung, TJ Choi - BMC immunology, 2008 - Springer
Background Signal transducer and activator of transcription 1 (STAT1) is a critical
component of interferon (IFN)-alpha/beta and IFN-gamma signaling. Although seven …

Molecular cloning and expression analysis of signal transducer and activator of transcription (STAT) from the Chinese white shrimp Fenneropenaeus chinensis

C Sun, HL Shao, XW Zhang, XF Zhao… - Molecular biology reports, 2011 - Springer
Innate immunity is the first line of defense by a host against invading pathogens. Several
signaling pathways participate in the immune response, one of which is the Janus kinase …

JAK/STAT signalling regulates antimicrobial activities in Eriocheir sinensis

Z Ruan, Z Wan, L Yang, W Li, Q Wang - Fish & shellfish immunology, 2019 - Elsevier
The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signalling
pathway plays a significant role in immune responses to pathogens. In invertebrates, three …