Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1
J Kim, RG Urban, JL Strominger, DC Wiley - Science, 1994 - science.org
The three-dimensional structure of a Staphylococcus aureus superantigen, toxic shock
syndrome toxin-1 (TSST-1), complexed with a human class II major histocompatibility …
syndrome toxin-1 (TSST-1), complexed with a human class II major histocompatibility …
Bacterial toxins as probes for the T-cell antigen receptor
B Fleischer - Immunology Today, 1989 - cell.com
A variety of microorganisms producesubstances with suppressive or stimulatinq effects on
cells of the immune system; these products also im% ence the pathogenesis of these …
cells of the immune system; these products also im% ence the pathogenesis of these …
The α1 domain of the HLA-DR molecule is essential for high-affinity binding of the toxic shock syndrome toxin-1
DR Karp, CL Teletski, P Scholl, R Geha, EO Long - Nature, 1990 - nature.com
SEVERAL exoproteins from the bacterium Staphylococcus aureus are highly potent
polyclonal activators of T cells in the presence of cells bearing class II antigens of the major …
polyclonal activators of T cells in the presence of cells bearing class II antigens of the major …
T lymphocyte activation by staphylococcal enterotoxins: role of class II molecules and T cell surface structures
B Fleischer, H Schrezenmeier, P Conradt - Cellular immunology, 1989 - Elsevier
The enterotoxins produced by Staphylococcus aureus (SE) are the most potent mitogens
known. Triggering of proliferation or cytotoxicity by SE requires the presence of MHC class II …
known. Triggering of proliferation or cytotoxicity by SE requires the presence of MHC class II …
Superantigen vaccines: a comparative study of genetically attenuated receptor-binding mutants of staphylococcal enterotoxin A
S Bavari, B Dyas, RG Ulrich - Journal of Infectious Diseases, 1996 - academic.oup.com
Superantigens exert their pathologic effects by direct binding to major histocompatibility
complex (MHC) class II molecules and T cell antigen receptors (TCR), thus circumventing …
complex (MHC) class II molecules and T cell antigen receptors (TCR), thus circumventing …
Major histocompatibility complex class I molecule serves as a ligand for presentation of the superantigen staphylococcal enterotoxin B to T cells.
AC Häffner, K Zepter, CA Elmets - Proceedings of the …, 1996 - National Acad Sciences
Superantigens, such as staphylococcal enterotoxin B (SEB), elicit a strong proliferative
response in T cells when presented in the context of major histocompatibility complex (MHC) …
response in T cells when presented in the context of major histocompatibility complex (MHC) …
Conservation of the biologically active portions of staphylococcal enterotoxins C1 and C2
GA Bohach, PM Schlievert - Infection and immunity, 1989 - Am Soc Microbiol
We determined the primary sequence of staphylococcal enterotoxin (SE) C2 by sequencing
its cloned structural gene, entC2. The entC2 structural gene contains an 801-base-pair open …
its cloned structural gene, entC2. The entC2 structural gene contains an 801-base-pair open …
Superantigens: just like peptides only different
The exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes are
prototype molecules for the larger family of superantigens (SAGs). This family now includes …
prototype molecules for the larger family of superantigens (SAGs). This family now includes …
Staphylococcal exotoxin activation of T cells. Role of exotoxin-MHC class II binding affinity and class II isotype.
JA Mollick, M Chintagumpala, RG Cook… - Journal of immunology …, 1991 - journals.aai.org
Staphylococcal enterotoxins (SE) and toxic shock syndrome toxin-1 bind directly to class II
molecules of the MHC and stimulate T cells based predominantly on the V beta segment …
molecules of the MHC and stimulate T cells based predominantly on the V beta segment …
[HTML][HTML] Complete amino acid sequence of staphylococcal enterotoxin A.
IY Huang, JL Hughes, MS Bergdoll… - Journal of Biological …, 1987 - Elsevier
The amino acid sequence of staphylococcal enterotoxin A is presented. Staphylococcal
enterotoxin A is a single-chain polypeptide which consists of 233 amino acid residues with a …
enterotoxin A is a single-chain polypeptide which consists of 233 amino acid residues with a …