[HTML][HTML] Amphipathic peptide antibiotics with potent activity against multidrug-resistant pathogens
J Shi, C Chen, D Wang, Z Tong, Z Wang, Y Liu - Pharmaceutics, 2021 - mdpi.com
The emergence and prevalence of multidrug-resistant (MDR) bacteria have posed a serious
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …
[HTML][HTML] Characterization of antimicrobial peptides toward the development of novel antibiotics
W Aoki, M Ueda - Pharmaceuticals, 2013 - mdpi.com
Antimicrobial agents have eradicated many infectious diseases and significantly improved
our living environment. However, abuse of antimicrobial agents has accelerated the …
our living environment. However, abuse of antimicrobial agents has accelerated the …
De novo generation of short antimicrobial peptides with enhanced stability and cell specificity
H Kim, JH Jang, SC Kim, JH Cho - Journal of Antimicrobial …, 2014 - academic.oup.com
Abstract Objectives Though antimicrobial peptides (AMPs) show great potential as novel
antibiotics, therapeutic applications are hindered by their low stability, toxicity and high …
antibiotics, therapeutic applications are hindered by their low stability, toxicity and high …
Antimicrobial peptides, an alternative antimicrobial agent against multi-drug-resistant microbes: Source, application, and potential
Pathogenic microorganisms are often associated with infectious diseases in humans, plants,
or animals. Over the past 100 years, antibiotics have been often used to combat the …
or animals. Over the past 100 years, antibiotics have been often used to combat the …
Host defense peptide mimicking peptide polymer exerting fast, broad spectrum, and potent activities toward clinically isolated multidrug-resistant bacteria
S Chen, X Shao, X Xiao, Y Dai, Y Wang… - ACS Infectious …, 2020 - ACS Publications
Multidrug-resistant (MDR) bacteria have emerged quickly and have caused serious
nosocomial infections. It is urgent to develop novel antimicrobial agents for treating MDR …
nosocomial infections. It is urgent to develop novel antimicrobial agents for treating MDR …
[HTML][HTML] Antimicrobial and antibiofilm activity of UP-5, an ultrashort antimicrobial peptide designed using only arginine and biphenylalanine
The recent upsurge of multidrug resistant bacteria (MDRB) among global communities has
become one of the most serious challenges facing health professionals and the human …
become one of the most serious challenges facing health professionals and the human …
The design and functional characterization of the antimicrobial and antibiofilm activities of BMAP27-melittin, a rationally designed hybrid peptide
A Almaaytah, S Tarazi, M Al-Fandi, A Abuilhaija… - International Journal of …, 2015 - Springer
BMAP-27 and melittin are two antimicrobial peptides (AMPs) that display potent
antimicrobial activities against a wide range of microbes including multidrug resistant (MDR) …
antimicrobial activities against a wide range of microbes including multidrug resistant (MDR) …
New antimicrobial peptides with repeating unit against multidrug-resistant bacteria
C Zhong, F Zhang, J Yao, Y Zhu, N Zhu… - ACS Infectious …, 2021 - ACS Publications
With the aim of tackling the increasingly serious antimicrobial resistance and improving the
clinical potential of AMPs, a facile de novo strategy was adopted in this study, and a series of …
clinical potential of AMPs, a facile de novo strategy was adopted in this study, and a series of …
[HTML][HTML] The antimicrobial peptide LI14 combats multidrug-resistant bacterial infections
J Shi, C Chen, D Wang, Z Wang, Y Liu - Communications Biology, 2022 - nature.com
The prevalence of multidrug-resistant (MDR) pathogens raises public fears of untreatable
infections and represents a huge health risk. There is an urgent need to exploit novel …
infections and represents a huge health risk. There is an urgent need to exploit novel …
[HTML][HTML] Hydrophilic/hydrophobic characters of antimicrobial peptides derived from animals and their effects on multidrug resistant clinical isolates
LIU Cun-Bao, S Bin, BAI Hong-Mei, T Jing… - Zoological …, 2015 - ncbi.nlm.nih.gov
Multidrug resistant (MDR) pathogen infections are serious threats to hospitalized patients
because of the limited therapeutic options. A novel group of antibiotic candidates …
because of the limited therapeutic options. A novel group of antibiotic candidates …