Hybridization and antibiotic synergism as a tool for reducing the cytotoxicity of antimicrobial peptides
A Almaaytah, MT Qaoud, A Abualhaijaa… - Infection and drug …, 2018 - Taylor & Francis
Introduction: As the development of new antimicrobial agents faces a historical decline, the
issue of bacterial drug resistance has become a serious dilemma that threatens the human …
issue of bacterial drug resistance has become a serious dilemma that threatens the human …
Antimicrobial peptides: a promising avenue for human healthcare
GM Bhopale - Current pharmaceutical biotechnology, 2020 - ingentaconnect.com
Antimicrobial drugs resistant microbes have been observed worldwide and therefore
alternative development of antimicrobial peptides has gained interest in human healthcare …
alternative development of antimicrobial peptides has gained interest in human healthcare …
Synergistic activity profile of an antimicrobial peptide against multidrug‐resistant and extensively drug‐resistant strains of Gram‐negative bacterial pathogens
S Pollini, J Brunetti, S Sennati… - Journal of Peptide …, 2017 - Wiley Online Library
Infection sustained by multidrug‐resistant and extensively drug‐resistant bacterial
pathogens is often untreatable with the standard of care antibiotics, and the combination of …
pathogens is often untreatable with the standard of care antibiotics, and the combination of …
[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides
Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …
Discovery, optimization, and clinical application of natural antimicrobial peptides
Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally
diverse molecules are produced as the first line of defense against pathogens such as …
diverse molecules are produced as the first line of defense against pathogens such as …
Functional and toxicological evaluation of MAA-41: a novel rationally designed antimicrobial peptide using hybridization and modification methods from LL-37 and …
Background: Managing bacterial infections caused by multidrug-resistant (MDR) and
biofilmforming bacteria is a global health concern. Therefore, enormous efforts were directed …
biofilmforming bacteria is a global health concern. Therefore, enormous efforts were directed …
Antimicrobial peptides–antibiotics combination: An effective strategy targeting drug‐resistant Gram‐negative bacteria
F Zhang, C Zhong, J Yao, J Zhang, T Zhang… - Peptide …, 2022 - Wiley Online Library
To address the growing resistance of Gram‐negative bacteria and enhance the clinical
application potential of antimicrobial peptides. In this study, we combined two α‐helical …
application potential of antimicrobial peptides. In this study, we combined two α‐helical …
[HTML][HTML] Antibacterial activity of peptides and bio-safety evaluation: in vitro and in vivo studies against bacterial and fungal pathogens
MV Arasu, NA Al-Dhabi - Journal of Infection and Public Health, 2023 - Elsevier
Background Antimicrobial peptides are promising alternatives to antibiotics to treat bacterial
and fungal infections, especially drug-resistant clinical pathogens. Methods Antimicrobial …
and fungal infections, especially drug-resistant clinical pathogens. Methods Antimicrobial …
A review of antimicrobial peptides: its function, mode of action and therapeutic potential
S Nayab, MA Aslam, S Rahman, ZD Sindhu… - International Journal of …, 2022 - Springer
Antimicrobial peptides (AMPs) are endogenous polypeptides produced by multicellular
organisms in order to protect a host from pathogenic microbes. AMPs are also defined as …
organisms in order to protect a host from pathogenic microbes. AMPs are also defined as …
A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and …
MF Mohamed, A Brezden, H Mohammad… - Scientific Reports, 2017 - nature.com
Antimicrobial peptides (AMPs) represent a promising therapeutic alternative for the
treatment of antibiotic-resistant bacterial infections. The present study investigates the …
treatment of antibiotic-resistant bacterial infections. The present study investigates the …