Peptide therapeutics versus superbugs: highlight on current research and advancements
K Nagarajan, SK Marimuthu, S Palanisamy… - International Journal of …, 2018 - Springer
Antibiotics have saved several millions of lives, but its persistent use of antibiotics in the
treatment of various infections, whether bacterial, fungal, viral or parasitic has lead to the …
treatment of various infections, whether bacterial, fungal, viral or parasitic has lead to the …
Design and synthesis of broad-spectrum antimicrobial amphiphilic peptidomimetics to combat drug-resistance
Y Chen, Z Ye, W Zhen, L Zhang, X Min, Y Wang… - Bioorganic …, 2023 - Elsevier
The gradual depletion of antibiotic discovery pipeline makes the antibiotic resistance a
difficult clinical problem and a global health emergency. The membrane-active antimicrobial …
difficult clinical problem and a global health emergency. The membrane-active antimicrobial …
Bactericidal activity against meticillin-resistant Staphylococcus aureus of a novel eukaryotic therapeutic recombinant antimicrobial peptide
Q Li, J Huang, H Guo, X Guo, Y Zhu, K Dong - International journal of …, 2012 - Elsevier
Antimicrobial peptides (AMPs) are one of several potential antibacterial agents in the current
era of antibiotics facing severe challenges. In this study, the bactericidal activity and stability …
era of antibiotics facing severe challenges. In this study, the bactericidal activity and stability …
[HTML][HTML] Synthetic antimicrobial peptides: Characteristics, design, and potential as alternative molecules to overcome microbial resistance
PG Lima, JTA Oliveira, JL Amaral, CDT Freitas… - Life Sciences, 2021 - Elsevier
Recently, the dramatic emergence of antimicrobial resistance has received attention from
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …
World Health Organization. Synthetic antimicrobial peptides (SAMPs) are considered new …
Combating Antimicrobial Resistance by Employing Antimicrobial Peptides: Immunomodulators and Therapeutic Agents against Infectious Diseases
I Mehraj, A Hamid, U Gani, N Iralu… - ACS Applied Bio …, 2024 - ACS Publications
The rising prevalence of multiple-drug-resistant pathogens poses a formidable challenge to
conventional antimicrobial treatments. The inability of potent antibiotics to combat these …
conventional antimicrobial treatments. The inability of potent antibiotics to combat these …
Antimicrobial peptides
PR Hansen - Methods Mol Biol. Humana Press, New York, NY, 2017 - Springer
Antibiotics have saved millions of lives and helped shape modern medicine. However, the
emergence of multidrug-resistant pathogens has become a global health problem, and …
emergence of multidrug-resistant pathogens has become a global health problem, and …
In vitro activity of novel in silico‐developed antimicrobial peptides against a panel of bacterial pathogens
AA Romani, MC Baroni, S Taddei… - Journal of Peptide …, 2013 - Wiley Online Library
Antimicrobial‐peptide‐based therapies could represent a reliable alternative to overcome
antibiotic resistance, as they offer potential advantages such as rapid microbicidal activity …
antibiotic resistance, as they offer potential advantages such as rapid microbicidal activity …
Designing peptide amphiphiles as novel antibacterials and antibiotic adjuvants against gram-negative bacteria
H Xing, V Loya-Perez, J Franzen, PW Denton… - Bioorganic & Medicinal …, 2023 - Elsevier
Gram-negative strains are intrinsically resistant to most antibiotics due to the robust and
impermeable characteristic of their outer membrane. Self-assembling cationic peptide …
impermeable characteristic of their outer membrane. Self-assembling cationic peptide …
Recent approaches in design of peptidomimetics for antimicrobial drug discovery research
S Lohan, G Singh Bisht - Mini reviews in medicinal chemistry, 2013 - ingentaconnect.com
Resistant pathogenic microbial strains are emerging at a rate that far exceeds the pace of
new anti-infective drug development. In order to combat resistance development, there is …
new anti-infective drug development. In order to combat resistance development, there is …
Recent development of small antimicrobial peptidomimetics
Y Niu, RE Wang, H Wu, J Cai - Future medicinal chemistry, 2012 - Taylor & Francis
Antimicrobial peptides (AMPs) hold promise to circumvent the emergence of drug resistance
occurring in the treatment of bacteria using many conventional antibiotics. Antimicrobial …
occurring in the treatment of bacteria using many conventional antibiotics. Antimicrobial …