Uniform-sized amino-modified silica nanoparticles have been prepared by the controlled
synchronous hydrolysis of tetraethoxysilane and N-(β-amimoethyl)-γ …

In this paper we report a novel DNA‐enrichment technology based on amino‐modified
functionalized silica nanoparticles. The approach takes advantage of the amino‐modified …

In order to develop a safe and effective gene therapy carrier, some toxicological and
biodynamical experiments were carried out on silica nanoparticles (SiNPs). First we …

Finding and exploiting safe and high-efficiency gene carriers have always been critical tasks
for gene therapy. In this work, novel GSH-triggered degradable organosilica nanoparticles …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

A new method is proposed for the fabrication of fluorescence-labeled and amine-modified
silica nanoparticles for application as nonviral vectors in gene delivery. Highly …

The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

DNA delivery is a core technology for gene structure and function research as well as
clinical settings. The ability to safely and efficiently targeted transfer foreign DNA into cells is …

Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …

BACKGROUND & OBJECTIVE: Poly-l-lysine-modified silica nanoparticle (PMS-NP) was a
novel non-viral vector for gene delivery. The current study was designed to evaluate the …