Trained immunity: long-term adaptation in innate immune responses
H Tercan, NP Riksen, LAB Joosten… - … and Vascular Biology, 2021 - Am Heart Assoc
Adaptive immune responses are characterized by antigen specificity and induction of
lifelong immunologic memory. Recently, it has been reported that innate immune cells can …
lifelong immunologic memory. Recently, it has been reported that innate immune cells can …
Regulatory T cell memory
MD Rosenblum, SS Way, AK Abbas - Nature Reviews Immunology, 2016 - nature.com
Memory for antigen is a defining feature of adaptive immunity. Antigen-specific lymphocyte
populations show an increase in number and function after antigen encounter and more …
populations show an increase in number and function after antigen encounter and more …
Memory-T-cell-derived interferon-γ instructs potent innate cell activation for protective immunity
SMH Soudja, C Chandrabos, E Yakob, M Veenstra… - Immunity, 2014 - cell.com
Cells of the innate immune system are essential for host defenses against primary microbial
pathogen infections, yet their involvement in effective memory responses of vaccinated …
pathogen infections, yet their involvement in effective memory responses of vaccinated …
Immunological memory to viral infections
▪ Abstract The purpose of immunological memory is to protect the host from reinfection, to
control persistent infections, and, through maternal antibody, to protect the host's …
control persistent infections, and, through maternal antibody, to protect the host's …
Surviving the crash: transitioning from effector to memory CD8+ T cell
LM D'Cruz, MP Rubinstein, AW Goldrath - Seminars in immunology, 2009 - Elsevier
One outcome of infection is the formation of long-lived immunological memory, which
provides durable protection from symptomatic re-infection. In response to infection or …
provides durable protection from symptomatic re-infection. In response to infection or …
The molecular basis of the memory T cell response: differential gene expression and its epigenetic regulation
N Weng, Y Araki, K Subedi - Nature Reviews Immunology, 2012 - nature.com
How the immune system remembers a previous encounter with a pathogen and responds
more efficiently to a subsequent encounter has been one of the central enigmas for …
more efficiently to a subsequent encounter has been one of the central enigmas for …
[HTML][HTML] The role of cell metabolism in innate immune memory
AV Ferreira, J Domiguéz-Andrés… - Journal of Innate Immunity, 2022 - karger.com
Immunological memory is classically attributed to adaptive immune responses, but recent
studies have shown that challenged innate immune cells can display long-term functional …
studies have shown that challenged innate immune cells can display long-term functional …
Long-term reprogramming of the innate immune system
J Dominguez-Andres, MG Netea - Journal of leukocyte biology, 2019 - academic.oup.com
During the last few years, a growing body of evidence has shown that immunological
memory is not an exclusive trait of lymphocytes, as many inflammatory insults can alter the …
memory is not an exclusive trait of lymphocytes, as many inflammatory insults can alter the …
Innate immune memory: implications for host responses to damage‐associated molecular patterns
Cells of the innate immune system build immunological memory via epigenetic
reprogramming after stimulations with microbial ligands. This functional readjustment allows …
reprogramming after stimulations with microbial ligands. This functional readjustment allows …
Potential role of gut microbiota in induction and regulation of innate immune memory
The gut microbiota significantly regulates the development and function of the innate and
adaptive immune system. The attribute of immunological memory has long been linked only …
adaptive immune system. The attribute of immunological memory has long been linked only …